IV Induction Agents

Question 1

pH 7.0
pKa 11
VD (L/kg) 4
Protein binding % 98
Cl (ml/kg/min) 30-60
Mol Wt 178.28

Answer 1

Propofol

Question 2

pH 10.5
pKa 7.6
VD (L/kg) 2.2
Protein binding % 80
Cl (ml/kg/min) 3.5
Mol Wt 264.32

Answer 2

Thiopental

Question 3

pH 3.4-5.5
pKa 7.5
VD (L/kg) 3
Protein binding % 25
Cl (ml/kg/min) 17
Mol Wt 238

Answer 3

Ketamine

Question 4

pH 8.1
pKa 4.8
VD (L/kg) 3
Protein binding % 75
Cl (ml/kg/min) 10-20
Mol Wt 342.3

Answer 4

Etomidate