Ivan Slides

Question 1

Bifid uvula: minimal manifestation of what?

Answer 1

Cleft palate

Question 2

Pierre Robin sequence: What are the three characteristics?

Answer 2

1. Mandibular micrognathia
2. Glossptosis with airway obstruction
3. Cleft palate

Question 3

With Pierre Robin sequence, there is constraint of mandibular growth in utero. This results in failure of the tongue to descend, causing what two issue?

Answer 3

1. Fusion of palatal shelves

2. Adequate respiration

Question 4

What is the mortality rate for Pierre Robin?

Answer 4

2-12% (usually due to respiratory issues)

Question 5

Paramedian lip pits usually invaginate which lip?

Answer 5

Lower

Question 6

What gene is impacted causing Paramedian lip pits?

Answer 6

IRF6

Question 7

What syndrome are paramedian lip pits the most common manifestation of?

Answer 7

van der Woude syndrome

Question 8

What is the prevalence of Commisural lip pits in adults and children?

Answer 8

Adults: 10-20%
Children: <1%

Question 9

Where are commissural lip pits?

Answer 9

At the corners of the mouth on vermillion border in depth?

Question 10

What syndrome is double lip occasionally associated with?

Answer 10

Ascher syndrome

Question 11

How prevalent is fissured tongue?

Answer 11

2-5%

Question 12

How many children die from complications due to Beckwith-Wiedemann syndrome?

Answer 12

10-20%

Question 13

What is (generally) Beckwith-Wiedemann syndrome?

Answer 13

A pediatric overgrowth disorder associated with predisposition to cancer

Question 14

How rare is an ectopic thyroid at base of tongue?

Answer 14

1 in 100K people (with a female predilection)

Question 15

What is the most common symptom of an ectopic thyroid at the base of tongue?

Answer 15

Dysphagia

Question 16

In greater than what percent of patients is the lingual thyroid the only thyroid tissue for an ectopic thyroid at the base of the tongue?

Answer 16

75%

Question 17

For a thyroglossal duct cyst, how common is it in infancy/childhood?

Answer 17

2.2: 100,000

Question 18

In what percent of patients of thyroglossal duct cyst is the cyst located in the infrahyoid position and it moves up and down with swallowing?

Answer 18

75%

Question 19

What is the most common non-odontogenic cyst of the gnathic bones?

Answer 19

Nasopalatine duct cyst (incisive canal cyst)

Question 20

What causes the median palatal cyst to develop?

Answer 20

It comes from entrapped epithelium during the embryologic fusion of palatal processes

Question 21

What is the most common branchial cleft anomaly?

Answer 21

The branchial cleft cyst

Question 22

What is the second most common branchial cleft cyst at 90%?

Answer 22

Second branchial cleft cyst?

Question 23

How much more common is coronoid hyperplasia in men compared to women?

Answer 23

5:1

Question 24

How much more common in women than men is condylar hyperplasia?

Answer 24

3 times

Question 25

Where are 85% of Stafne defects found?

Answer 25

In the posterior body of the mandible beneath the inferior alveolar canal

Question 26

Where are 10 to 15% of Stafne defects found?

Answer 26

The anterior mandible (and associated with sublingual gland)

Question 27

How much more common is the Stafne defect in men compared to women?

Answer 27

6:1

Question 28

Where are lateral soft palata fistulas most common?

Answer 28

Anterior tonsillar pillars, bilaterally

Question 29

What percent are children at risk for cancer in connection with isolated lateralized overgrowth (hemihyperplasia)?

Answer 29

5%

Question 30

During what decades is the onset of Parry-Romberg syndrome?

Answer 30

First to second

Question 31

How long does the bone in Parry-Romberg syndrome atrophy before it stabilizes?

Answer 31

5-20 years

Question 32

How common is Crouzon syndrome?

Answer 32

1 in 65K

Question 33

What gene is mutated to cause Crouzon syndrome?

Answer 33

FGFR2

Question 34

What branch/es is/are responsible for Treacher Collins syndrome (mandibulofacial dysostosis)?

Answer 34

1st and 2nd

Question 35

What gene is implicated in Treacher Collins syndrome (mandibulofacial dysostosis)?

Answer 35

TCOF1

Question 36

Some cleft palates may present as what type of clefts only?

Answer 36

Submucosal