Flashcards in IX - General Pathology of Infectious Diseases Deck (24)
2
These agents cause transmissible spongiform encephalopathies.
Prions
p. 321
3
Infected cells show distinct nuclear and ill-defined cytoplasmic inclusions.
CMV
p. 322
4
Infected cells show glassy nuclear inclusions, frequently with a surrounding halo.
Herpesvirus infection
p. 322
5
Infected hepatocytes show diffuse granular (ground-glass) cytoplasm.
Hepatitis B viral infection
p. 322
6
Sexually transmitted protozoan that can colonize the vagina and male urethra.
Trichimonas vaginalis
p. 325
7
Protozoan acquired either by contact with oocyte-shedding kittens or by consumption of cyst-ridden undercooked meat.
Toxoplasma gondii
p. 325
8
Size of microorganisms for them to be inhaled directly into the alveoli.
5 um
p. 327
9
These microorganisms grow in contaminated food and releases powerful enterotoxins that cause food poisoning symptoms without any bacterial multiplication in the gut.
Staphylococcal strains
p. 327
10
Intestinal helminth that cause disease when present in large numbers or cause obstruction of the gut.
Ascaris lumbricoides
p. 326
11
Helminth that causes iron deficiency anemia by chronic loss of blood.
Hookworms
p. 327
12
Helminth that depletes vitamin B12 giving rise to an illness resembling pernicious anemia.
Diphyllobotrium latum
p. 327
13
Placentofetal route as a mode of transmission is also referred to as ________.
Vertical transmission
p. 329
14
The ability of bacteria to cause disease.
Virulence
p. 331
15
Bacterial surface molecules that bind to host cells.
Adhesins
p. 332
16
Filamentous proteins on gram negative bacteria which allow exchange of genes between bacteria, and also involved in adherence.
Fimbriae/pili
p. 332
17
Clostridium perfringens produces this toxin that disrupts plasma membranes resulting in digestion of host tissues and collagen.
Alpha toxin (lecithinase)
p. 334
18
Bacterial toxins with the capacity to stimulate large populations of T lymphocytes, functionally resulting in a "cytokine storm".
Superantigens
p. 334
19
Examples of antigen presenting cells.
Dendritic cellsMacrophagesB-cells
p. 334
20
A superantigen secreted by S. aureus which causes inflammation, fever and shock. Found in the vagina of menstruating women.
Toxic shock syndrome toxin (TSST-1)
p. 334
21
Collection of neutrophils which gives rise to localized liquefactive necrosis.
Abscess
p. 334
22
High risk agents of bioterrorism which are easily disseminated and has high potential for mortality. An example is smallpox.
Category A
23
A distinctive form of mononuclear inflammation usually evoked by infectious agents that resist eradication, but are capable of stimulating strong T cell mediated immunity. Characterized by epitheloid cells which may fuse to form giant cells.
Granulomatous inflammation
p. 335
24
Agents that are relatively easy to disseminate and produces moderate morbidity and low mortality. An example is E.coli O157:H7 which can cause HUS.
Category B
25