Jaundice

Question 1

Prehepatic jaundice
Unconjugated and conjugated bilirubin in serum?
Urine bilirubin?
Stool urobilinogen?
Urine urobilinogen?

Answer 1

Serum - unconjugated = increased
Serum - conjugated = normal
Urine bilirubin = negative

Stool urobilinogen = increased
Urine urobilinogen = increased

Question 2

What diseases/conditions are associated with pre-hepatic jaundice?

Answer 2

Hemolytic anemia
Gilbert’s syndrome (cannot conjugate bilirubin)

Question 3

Hepatic jaundice
Unconjugated and conjugated bilirubin in serum?
Urine bilirubin?
Stool urobilinogen?
Urine urobilinogen?

Answer 3

Serum - unconjugated = increased
Serum - conjugated = increased
Urine bilirubin = positive (you’ll see the unconjugated/direct type bc this one is water soluble)

Stool urobilinogen = variable
Urine urobilinogen = increased