Joints, synovial fluid and cartilage Flashcards

(34 cards)

1
Q

What are the three types of joints

A

Fibrous
Cartilagenous
Synovial

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2
Q

Describe fibrous joints

A

Not much movement
Strong
Collagen fibres inbetween bones

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3
Q

Where are fibrous joints found

A

Found in skull (periodontal ligament and cranial sutures

Also interosseous membrane

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4
Q

Describe cartilaginous joints

A

Cartilage between

Primary or secondary

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5
Q

Describe a primary cartilaginous joint

A

Only hyaline cartilage – SYNCHONDROSIS

Found on growth plate

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6
Q

Describe a secondary cartilaginous joint

A

hyaline & fibrocartilage – SYMPHYSIS

Found in intervertebral disc

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7
Q

What are the types of synovial joint

A
  • Hinge, Pivot, Saddle, Plane, Condylar, Ball and socket
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8
Q

What determines joint stability

A

Shape of articulating surfaces
Fibrous capsule and ligaments
Muscles
Cartilage (in synovial joints)

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9
Q

What is the type of cartilage found in synovial joints

A

Fibrocartilage

Hyaline cartilage

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10
Q

What does fibrocartilage look like and what is its function in synovial joints

A

Half moon shaped menisci which make the articulating surfaces fit better (increases movement and stability). They also play a role in shock absorption (because they are made up on fibrocartilage (v strong).

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11
Q

What does hyaline cartilage look like and what is its function in synovial joints

A

Hyaline cartilage : found In articular surfaces of joints. Also contains collagen but not as densely bound and so it weaker.

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12
Q

What kind of proteins are found in joints

A

Glycoprotein
Proteoglycans
Glycosaminoglycans

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13
Q

What is a glycoprotein

A

Glycoproteins (e.g. lubricin): proteins to which oligosaccharide chains are attached, i.e. more a protein than a carbohydrate!

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14
Q

What is a proteoglycan

A
  • Proteoglycans (e.g. aggrecan): proteins that are heavily glycosylated (= a protein core to which one or more GAGs attach), i.e. tend to be more carb than protein!-
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15
Q

What is a Glycosaminoglycans

A

Glycosaminoglycans or GAGs (e.g. hyaluronic acid): long unbranched polysaccharides, which are highly polar and thus attract water (helps maintain high water content)

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16
Q

What is a chondrocyte

A

A cartilage cell

17
Q

What do the chondrocytes look like and what to do they do at the superficial layer of hyaline cartilage

A

They are flattened and produce collagen and glycoproteins (lubricin)

18
Q

What do the chondrocytes look like and what to do they do at the transitional/deep layer of hyaline cartilage

A

They are round and produce proteoglycans (aggrecan)

19
Q

What % of hyaline cartilage is water and why is this important

A

> 75% water

Water is incompressible

20
Q

What 3 A words are used to describe cartilage

A

Avascular
Aneural
Alymphatic

21
Q

How does cartilage get its nutrients

A

The synovial fluids help provide nutrients to the cartilage. . It also helps with lubrication (less friction)

22
Q

Where is synovial fluid made

A

It is produced by synoviocytes in the synovial membrane (the synovium)

23
Q

Describe the synovium

A

Synoviocytes producing the fluid
Rich capillary network
No epithelial lining

24
Q

What exchanges at the synovium

A

Direct exchange of oxygen, carbon dioxide & metabolites between blood & synovial fluid

25
What are the categories of synoviocyte
Type A | Type B
26
Describe type A synoviocytes
Look like macrophages Remove debris from tissue Contribute to synovial fluid production
27
Describe type B synoviocytes
Fibroblast like Main producer of synovial fluid
28
What does synovial fluid contain
Contains Hyaluronic acid & lubricin
29
How long does it take to turnover synovial fluid
2 hours (rapid)
30
What are the types of lubrication at a joint
Boundary Hydrodynamic Weeping
31
What is boundary lubrication
Glycoproteins such as lubricin bind to receptors on articular surfaces to form a thin film Hydrodynamic (like aquaplaning)
32
What is Hydrodynamic lubrication
Surfaces kept apart by liquid pressure | Viscosity changes with load and velocity of movement
33
What is weeping lubrication
Fluid that is present in the cartilage is squeezed out into the synovial cavity to increase fluid volume
34
What happens to joints in the normal aging process
Viscosity of synovial fluid increases Slower joint movements Reduced lubrication Water content of cartilage decreases Reduced shock absorption