Kahoot Flashcards
The beta phase of a plasma concentration curve equals the redistribution from the plasma and VRG to the peripheral compartment.
False
alpha phase
A drug is considered cleared from the body when what percentage is cleared?
96.9%
You gave 300 mcg of a medication. After 3 half-lives, how much of a medication remains?
37.5 mcg
With first-order kinetics, half-life decreases as the drug plasma concentration decreases.
False
*half-life stays the same
There is an indirect relationship between clearance and what factor?
half-life
A drug with a hepatic extraction ratio of 0.1 is highly dependent on liver blood flow for clearance.
false
capacity dependent
Clearance for which drug below is highly dependent on liver blood flow.
a. Ketamine
b. Rocuronium
c. Methadone
d. Phenytoin
ketamine
What are two factors that affect glomerular filtration of drugs/metabolites?
GFR & protein binding
All of the following will affect clearance of drugs in the elderly population except:
a. decreased GFR
b. immature liver enzymes
c. decreased liver blood flow
d. increased fat
b. immature liver enzymes
What is true about passive tubular reabsorption?
a. drugs/metabolites move against a concentration gradient
b. it almost always requires energy
c. changing urine pH can change the amount of drug/metabolite reabsorbed
d. is highly dependent on the molecular weight of the drug
c. changing urine pH can change the amount of drug/metabolite reabsorbed
if the O:G is high, potency is also high.
true
If you are providing anesthesia to a child, you will need increased or decreased MAC?
increased
which anesthesia gas does not trigger malignant hyperthermia?
nitrous oxide
and Xenon
If a patient has a lower body temperature, they are quicker to wake up.
False
Which rarely used anesthesia gas is the least potent?
Xenon
