Kaplan Citric Acid Cycle And Oxidative Phosphorylation Flashcards
What is the name of the 1st complex in the ETC and what does it do
It is called NADH dehydrogenase and it convert NADH to NAD and translocate
The H ions to the intermembrane space
To creat the gradient
What are the by pass reactions that enter the ETC.
- Complex 2 succinate dehydrogenase
- Glycolysis FADH2
3.beta-oxidation (fatty Achl CoA dehydrogenase )
They all make a FADH2
What is the name if the lipid that carries the electrons in the ETC
Co-enzyme Q
What is the name of the 3nd complex of the ETC
It is cytochrome c/b2
What is name if the complex 4th of ETC
It is cytochrome a/a3
What is so special about the complex 4th
It has Fe oxidase that get rid of the H by binding it with O to form water
What is the name if the enzyme that form ATP
F0F1 ATP synthesis
What are the products or substance that do uncoupling oxidation phosphorylation
High does aspirin
Thermogenin(brown adipose )
2,4DNP
What are the drugs and toxins that effect the complex 1
Mnemonic
BiRds are eaten by Two Cats and an Owl
1-burbiturate
2_rotenone in insecticide
What are the drugs and toxins that effect complex 4th
CO and cyanide
BiRds are eaten by Two Cats and an Owl
What is the name if the drug that effect
F0F1 ATP synthesis
BiRds are eaten by Two Cats and an Owl
Oligomycin
What are the causes if the leigh syndrome
Any generic mutation in the oxidation phosphorylation
What does the cyanide do to the complex 4
It hold the Fe in Fe3 ferric which and prevent it from binding with Hydrogen ions
What is the treatment for the cyanide poisoning
By nitrites which will convert the hemoglobins to meth hemoglobins so thr cyanide binds to it instead of binding with complex 4
What does the free radicals prefers (ROS ) high oxygenated or low oxygenated environment
Low because they can become more
