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NURS 317 Pathophysiology and Pharmacology > Karch Chapter 52: Drugs affecting the Urinary Tract and the Bladder > Flashcards

Karch Chapter 52: Drugs affecting the Urinary Tract and the Bladder Flashcards

1
Q

what is the dosage for fosfomycin?
a. 1 g bid PO
b. 150mg TID PO
c. 100mg OD IV
d. one packet (3g) dissolved in water PO

A

d

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2
Q

What are the usual indications for fosfomycin?
a. treatment of BPH
b. treatment for bladder pain
c. treatment for bladder spasms
d. treatment of UTIS in patients over 12 y/o

A

d

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3
Q

What is the usual adult dosage for methenamine?
a. one pack PO once
b. 100mg PO q12h
c. 1 g bid or qid and HS PO
d. 500 mg PO at bedtime

A

c

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4
Q

What is the usual dosage of methenamine for patients 6-12 y/o?
a. 0.5-1g PO bid to qid
b 1g in three divided doses
c. 400 mg bid
d. 60 mg PO with full glass of water

A

a

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5
Q

What is the usual dosage of methenamine for patients under 6 y/o?
a. 50mg/kg/d PO in three divided doses
b. 25 mg/kg/d PO at HS
c. 100 mg PO q12h
d. 40mg/kg/d PO

A

a

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6
Q

What is the usual indications for methenamine?
a. treatment of UTIs
b. bladder pain
c. supression/elimination of bacteriuria associated with UTIs and anatomical abnormalities
d. chronic UTIs

A

c

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7
Q

What is the usual dosage of methylene blue?
a. 500 mg PO OD for 12 days
b. 65-130 mg PO tid with full glass of water
c. 500-750 mg PO bid with full glass of water
d. 1 g PO OD

A

b

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8
Q

What are the usual indications for methylene blue?
a. bladder pain associated with surgery
b. BPH
c. urinary incontinence
d. suppression or elimination of bacteriuria associated with UTIS and anatomical abnormalities

A

d

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9
Q

what is the usual adult dose for nitrofurantoin (macrodantin, macrobid)?
a. 1g PO OD
b. 25-50mg qid for 14 days
c. 50mg PO daily
d. 50-100 mg PO qid for 10-14 d or 100 mg PO bid for 7 d

A

d

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10
Q

what is the usual adult dose of Macrobid for chronic suppressive therapy?
a. 50-100mg PO HS
b. 500mg PO OD
c. 250 mg PO bid
d. 50-100mg SC OD

A

a

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11
Q

what is the pediatric dosing for nitrofurantoin?
a. 20mg PO in three divided doses
b. 5-7mg/kg/d in 4 divided doses
c.15mg/kg/d PO
d. 5mg PO HS

A

b

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12
Q

What is the pediatric dosing for nitrofurantoin for chronic suppressive therapy?
a. 2mg/kg/d PO
b. 50 mg PO HS
c. 160 mg PO in three divided doses
d. 1mg/kg/d PO in two doses

A

d

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13
Q

What are the usual indications for nitrofurantoin?
a. Treatment of complex UTIs and kidney infections
b. Treatment of UTIs caused by susceptible bacteria
c. chronic bladder irritation and inflammation
d. suppression/elimination of bacteriuria

A

b

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14
Q

What is the usual dosage of trimethoprim?
a. 50 mg PO q12h or 100 mg PO daily for 10 d
b. 1g PO OD
c. 100mg PO q12h or 200 mg PO daily for 10d
d. 500 mg PO q12h

A

c

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15
Q

What is the the usual indication for trimethoprim?
a. bladder spasms
b. nocturia
c. UTIs
d. anatomical bladder abnormalities

A

c

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16
Q

What is the usual adult dose for trimethoprim-sulfamethoxazole?
a. 160 mg TMP/800mg SMZ q12h for 10 d
b. 20 mg TMP/ 500mg SMZ q8h for 14 d
c. 1g SC OD
d. 100mg PO q12h

A

a

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17
Q

What is the usual pediatric dose for children 2 mo and older for trimethoprim-sulfamethoxazole?
a. 8mg/kg TMP 40mg/kg SMZ given in two divided doses q12h for 10d
b. 10mg /kg TMP 20mg/kg SMZ given in three divided doses q8h for 14 d
c. 100mg PO daily in two divided doses
d. 25mg/kg TMP 10mg/kg SMZ PO daily

A

a

18
Q

What is the usual indication for trimethoprim-sulfamethoxazole?
a. chronic kidney infections
b. bladder spasms
c. enlarged prostate
d. UTIs

A

d

19
Q

What is the usual dose for darifenacin?
a. 10mg/d PO can be increased to 15 mg/d
b. 7.5mg/d PO
c. 7.5mg/d PO can be increased to 15mg/d
d. 15 mg/d PO

A

c

20
Q

What is the usual indication for darifenacin?
a. anticholinergic, overactive bladder in patients with urinary urgency, incontinence or frequency
b. anticholinergic, bladder spasms
c. bladder pain
d. UTIs including chronic UTIs

A

a

21
Q

What is the usual dosage for fesoterodine?
a. initial dose 2mg/d PO, can increase to 8mg/d
b. initial dose 5mg/d PO, can increase to 10mg/d
c. initital dose 4mg/d PO, cn increase to 8mg/d
d. initial dose 8mg/d PO, can be increased to 12mg/d

A

c

22
Q

what are the usual indications for fesoterodine?
a. symptomatic relief of bladder spasms
b. overactive bladder with urgency, incontinence, and frequency
c. urinary tract pain and irritation
d. urinary incontinence due to age related changes

A

b

23
Q

What is the usual dosage for flavoxate?
a. 100-200 mg PO tid to qid
b. 50-75 mg PO tid
c. 1g PO OD
d. 500mg-750mg PO tid to qid

A

a

24
Q

what are the usual indications for flavoxate?
a. UTIs for patients >12y
b. bladder pain for patients >12
c. urinary bladder spasms in patients >12
d. overactive bladder in patients >12

A

c

25
Q

What is the usual oxybutynin ER dose?
a. 15 mg/d PO up to a max. 30mg/d, 5mg PO in divided doses
b. 5 mg/d PO up to a max. 30mg/d, 5mg PO in divided doses
c. 10 mg/d PO up to a max. 30mg/d, 5mg PO in divided doses
d. 20 mg/d PO up to a max. 30mg/d, 5mg PO in divided doses

A

b

26
Q

What is the usual dosage for oxybutynin transdermal patch?
a. Apply to dry, intact skin q4-5d
b. Appy to wet skin q 3-4d
c. Apply to dry, intact skin q 3-4d
d. Apply to dry, intact skin weekly

A

c

27
Q

What is the usual pediatric (>5y) dose for oxybutynin?
a. 10 mg PO bid up to a max 15 mg PO tid
b. 5mg PO bid up to a max 5mg PO tid
c. 5mg PO daily
d. 5 mg PO bid to to a max 10mg PO tid

A

b

28
Q

What is the usual dose for oxybutynin gel?
a. Apply 1ml to thigh, abdomen, or upper arm once q24h
b. Apply 1ml to thigh, abdomen, or upper arm once q8h
c. Apply 5ml to thigh, abdomen, or upper arm once q24h
d. Apply 0.5 ml to thigh, abdomen, or upper arm once q12h

A

a

29
Q

What is the usual pediatric (>6 y) for ER oxybuynin?
a. 10mg PO/d
b. 2.5 mg PO/d
c. 15mg PO/d
d. 5mg PO/d

A

d

30
Q

What are the usual indications for oxybutynin?
a. bladder spasm and overactive bladder
b. bladder spasms associated with infection
c. UTIs and bladder pain
d. urinary urgency and incontinence

A

a

31
Q

What is the usual dosage for solifenacin?
a. 10mg PO swallowed whole with water
b. 5-10mg PO swallowed whole with water
c. 10-15mg PO swallowed whole with water
d. 5mg PO swallowed whole with water

A

b

32
Q

What are the usual indications for solifenacin?
a. UTIS
b. bladder pain
c. bladder spasms
d. overactive bladder with urgency, frequency or incontinence

A

d

33
Q

What is the usual dose for tolterodine?
a. 5-10mg PO bid
b. 1-2mg PO bid
c. 2.5-5mg PO bid
d. 5 mg PO bid

A

b

34
Q

What is the usual dosage for tolterodine ER?
a. 5mg PO/d
b. 1mg PO bid
c. 2-4mg PO/d
d. 2mg PO/d

A

c

35
Q

What are the usual indications for tolterodine?
a. overactive bladder with urgency, frequency or incontinence
b. burning associated with UTIS
c. hematuria
d. bladder spasms

A

a

36
Q

What is the usual dosage of mirabegron?
a. 20mg/d PO
b. 50mg/d PO
c. 25-50mg/d PO
d. 50-100mg/d PO

A

c

37
Q

What are the usual indications for mirabegron?
a. urinary bladder spasms and overactive bladder
b. overactive bladder in children
c. chronic UTIs
d. overactive bladder with symptoms of urinary incontinence, frequency and urgency

A

d

38
Q

What is the usual dosage for phenazopyridine?
a. 100-200mg PO tid after meals for up to 2d
b. 50-100mg PO tid after meals for up to 3 d
c. 100-200mg PO tid after meals for up to 3 d
d. 50-100mg PO tid after meals for up to 2 d

A

a

39
Q

What is the usual pediatric (6-12y) dosage of phenazopyridine?
a. 12 mg/kg/d ort 350mg/m2/d PO, divided into 3 doses, no more than 2 d
b. 10mg /kg/d ort 350mg/m2/d PO, divided into 3 doses, no more than 2 d
c. 15 mg/kg/d ort 500 mg/m2/d PO, divided into 3 doses, no more than 2 d
d. 20 mg /kg/d ort 350mg/m2/d PO, divided into 3 doses, no more than 2 d

A

a

40
Q

What are the usual indications for phenazopyridine?
a. urinary bladder spasm with incontinence,
b. bladder pain with cystitits
c. discomfort with urinary tract trauma or infection
d. chronic UTIs

A

c

41
Q

What is the usual dosage for pentosan polysulfate sodium?
a. 50 mg PO tid on empty stomach
b. 75 mg PO tid on empty stomach
c. 25 mg PO tid on empty stomach
d. 100 mg PO tid on empty stomach

A

d

NURS 317 Pathophysiology and Pharmacology (1 decks)

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