Keloid Flashcards
(12 cards)
1
Q
What is a scar?
A
replacement of normal tissue by fibrous connective tissue
2
Q
Types of scars?
A
- Flat vs elevated
- hypertrophic vs atrophic
3
Q
When will you get a scar?
A
If the tissue defect reaches the dermis, the deeper, the higher the risk
Note: if only the epidermis is affected, complete healing without a scar is possible
4
Q
4 phases of wound healing?
A
- hemostasis
- inflammatory
- proliferative
- maturation
5
Q
Hemostasis phase of wound healing?
A
- Immediate; 0 to 2 days in length
- Thrombin converts to fibrinogen
- Coagulation from dilated vessels
6
Q
Inflammatory phase of wound healing?
A
- 2 to 4 days
- Characterized by pain, redness, heat, swelling, and loss of function at the site of injury
- If inflammation lasts longer than 48-72 hours, look for evidence of tissue damage or infection
- The body’s protective response to injury
7
Q
Proliferative phase of wound healing?
A
- 4 to 21 days
- Involves the rebuilding of tissue;
- Filling the wound by granulation, contracting the wound and converting the wound through epithelialization
- Includes remodeling; Strengthens
8
Q
Maturation phase of wound healing?
A
- Can take up to 2 years
- Wound gains tensile strength
, improves - Wound appears to be healed. Collagen production, reorganization will be ongoing for 2 years
9
Q
What is the pathology of scars?
A
- natural process and part of wound healing.
- results in production of tissue that is
structurally and functionally different from normal skin.
10
Q
Histology of a scar?
A
- scar tissue is composed of fibrous tissue and collagen protein fibril deposits, produced by fibroblasts.
- scar structure is thicker and denser than the surrounding normal skin tissue.
- Collagen makes up about 25% to 35% of the whole-body protein content.
11
Q
Triggers of scar formation?
A
- wound infection
- wound dehiscence
- manipulating the wound
- genetic predisposition
- repeated injuries
12
Q
A
