Ketogenesis

Question 0

What converts HMG-CoA into mevalonate?

Answer 0

HMG-CoA reductase

Question 1

Wht converts acetoacetyl-CoA into HMG-CoA?

Answer 1

HMG-CoA Synthase (cytosolic v version)

Question 2

Ketones bodies and cholesterol are made from what precursor?

Answer 2

HMG COA (which is made from Acetyl CoA for both)

Question 3

excessive fat burning in the liver creates what?

Answer 3

ketone bodies

Question 4

excessive sugar and insulin results in?

Answer 4

cholesterol

Question 5

Which is not a functional ketone body?

acetoacetate, Beta-hydroxybutryryate, Acetone

Answer 5

Acetone

Question 6

IN response to low carbohydrate what does ketogenesis o?

Answer 6

increased fat burning, increased gluconeogenesis, OHOT makes excess acetyl CoA, excess acetyl CoA turns into ketone bodies, Body uses the ketone bodies instead of glucose, GNG is diinished

Question 7

in the increase fat burning response to low carbohydrate, what happens?

Answer 7

more acetyl CoA (from OGOT) going to the Krebs cycle

Question 8

During a low carbohydrate state, increased gluconeogenesis results i what?

Answer 8

more amino acids are converted into glucose

more oxaloacetate stolen from the Krebs Cycle to make glucose

Question 9

during ketogenesis what does glucose stimulate and inhibit?

Answer 9

glucagon is stimulating fat burning and inhibiting liver glycolysis.

Question 10

Fat oxidation (OHOT) in the liver results in what?

Answer 10

???

Question 11

During ketogenesis what intermediates are stolen form the Krebs cycle?

Answer 11

oxaloacetate