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Biochemistry II exam II > Ketogenesis > Flashcards

Flashcards in Ketogenesis Deck (12):
0

Wht converts acetoacetyl-CoA into HMG-CoA?

HMG-CoA Synthase (cytosolic v version)

1

What converts HMG-CoA into mevalonate?

HMG-CoA reductase

2

Ketones bodies and cholesterol are made from what precursor?

HMG COA (which is made from Acetyl CoA for both)

3

excessive fat burning in the liver creates what?

ketone bodies

4

excessive sugar and insulin results in?

cholesterol

5

Which is not a functional ketone body?
acetoacetate, Beta-hydroxybutryryate, Acetone

Acetone

6

IN response to low carbohydrate what does ketogenesis o?

increased fat burning, increased gluconeogenesis, OHOT makes excess acetyl CoA, excess acetyl CoA turns into ketone bodies, Body uses the ketone bodies instead of glucose, GNG is diinished

7

in the increase fat burning response to low carbohydrate, what happens?

more acetyl CoA (from OGOT) going to the Krebs cycle

8

During a low carbohydrate state, increased gluconeogenesis results i what?

more amino acids are converted into glucose
more oxaloacetate stolen from the Krebs Cycle to make glucose

9

during ketogenesis what does glucose stimulate and inhibit?

glucagon is stimulating fat burning and inhibiting liver glycolysis.

10

Fat oxidation (OHOT) in the liver results in what?

???

11

During ketogenesis what intermediates are stolen form the Krebs cycle?

oxaloacetate