Flashcards in Ketogenesis Deck (12):
Wht converts acetoacetyl-CoA into HMG-CoA?
HMG-CoA Synthase (cytosolic v version)
What converts HMG-CoA into mevalonate?
Ketones bodies and cholesterol are made from what precursor?
HMG COA (which is made from Acetyl CoA for both)
excessive fat burning in the liver creates what?
excessive sugar and insulin results in?
Which is not a functional ketone body?
acetoacetate, Beta-hydroxybutryryate, Acetone
IN response to low carbohydrate what does ketogenesis o?
increased fat burning, increased gluconeogenesis, OHOT makes excess acetyl CoA, excess acetyl CoA turns into ketone bodies, Body uses the ketone bodies instead of glucose, GNG is diinished
in the increase fat burning response to low carbohydrate, what happens?
more acetyl CoA (from OGOT) going to the Krebs cycle
During a low carbohydrate state, increased gluconeogenesis results i what?
more amino acids are converted into glucose
more oxaloacetate stolen from the Krebs Cycle to make glucose
during ketogenesis what does glucose stimulate and inhibit?
glucagon is stimulating fat burning and inhibiting liver glycolysis.
Fat oxidation (OHOT) in the liver results in what?