Kidney and Bladder Neoplasm Flashcards Preview

FEK Y2 > Kidney and Bladder Neoplasm > Flashcards

Flashcards in Kidney and Bladder Neoplasm Deck (22):
1

"fall foliage" kidney tumor

renal adenocarcinoma appearance - due to vascularity and hemorrhage in the neoplasm

2

most common type of kidney tumor

renal adenocarcinoma

3

four types of renal adenocarcinoma

1. clear cell carcinoma 2. granular cell carcinoma 3. papillary tumors 4. sarcomatoid tumors

4

what is this?

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clear cell carcinoma, kidney

5

describe granular cell carcinoma

eosinophilic cytoplasm w/ granular texture (b/c lots of mitochondria and other cytoplasmic organelles)

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6

what is this?

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papillary adenocarcinoma

7

what is this?

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sarcomatoid carcinoma

spindle cell morphology

8

Nephroblastoma/Wilm's tumor - who gets it? 

Prognosis?

common in children 2-4yrs

prognosis = favorable.  anaplastic histology = bad. worse prognosis for older children

9

pathology of nephroblastoma/Wilm's tumor

large w/ fleshy, lobulated appearance - palpated on PE

undifferentiated cells 

anaplastic Wilm's: atypical nuclei w/ prominent nucleoli and mitotic activity = worse prognosis

 

10

what is this

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stromal cells in nephroblastoma

11

schistosomiasis causes what type of neoplasm?

transitional cell carcinoma of the bladder

12

field change concept

type or degree of histological change in the urothelium adjacent to or remote from a clinically detected tumor

13

renal cell carcinoma presentation

hematuria, pain, flank mass

systemic signs (fever, anemia, hepatic dysfunction, amyloidosis)

paraneoplastic syndromes

14

best predictor of renal cell carcinoma

stage (metastasis?)

15

natural hx of renal cell carcinoma

unpredictable

spontaneous regression (rare)

common locations of metastatic spread: lungs, bones

 

16

what is this?

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Wilm's tumor / nephroblastoma

17

urothelial transitional cell tumors - multiplicity and multicentricity

common for multiple tumors to pop up at the same or different time, in the same place or elsewhere in the tract b/c urothelium undergoes field change

18

what is the major risk factor for bladder cancer ?

smoking

19

how to dx bladder cancer?

histologic appearance

cytology, cystoscopy w/ biopsy

appearance: papillary like brocoli heads

20

what is this?

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bladder cancer

21

what is this?

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urothelial carcinoma-in-situ

no maturation from BM to top

22

upper urothelial tract cancer

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not as common as renal cell carcinoma

epi: elderly, more common in males

presentation: hematuria