Kidney Function Test Flashcards
(24 cards)
functions of the kidney
- urine formation
- fluid & electrolyte balance
- regulation of acid-base balance
- excretion of waste products of protein metabolism
- excretion of drugs & toxins
- secretion of hormones
hormones secreted by kidney
- renin
- erythropoietin
- 1,25 dihydroxy vit d3
- prostaglandins
total renal blood flow
1200-1500 mL/min
total renal plasma flow
600-700 mL/min
regulating functions of the nephron
- glomerular filtration
- tubular reabsorption
- tubular secretion
functional unit of the kidney
nephron
nephron is composed of a
renal corpuscle & a renal tubule
consists of a coil approx. 8 capillary lobes which has a wall
glomerulus
cup-like sack that performs the 1st step un the filtration of blood to form urine
Bowman’s capsule
non selective filtration of plasma w/ a MW of
66,000 DA
repels molecules w/ charge even they are small enough to pass
Shield of negativity
function of loop of henle
recovery of H2O & NaCl from the urine
hyperosmotic, large conc of solute
descending loop of henle
diluting segment, limited amount of solute
ascending loop of Henle
low permeability to ions & urea, while being highly permeable to h2o
descending loop of Henle
thin & thick segment, h2o impermeable.
ascending loop of henle
function of distal convoluted tubule
electrolyte & acid base homeostasis
final site for either concentrating or diluting of urine
Collecting ducts
major end product of protein & amino acid catabolism
BUN
percentage of BUN of total NPN
75%
BUN is synthesized from ____ form the destination of amino acids
liver
first metabolite to elevate in idney disease & is primarily removed through dialysis
BUN
conversion factor of BUN
0.357
fasting sample is required in BUN. true or false?
false