Kidneys Flashcards

(33 cards)

1
Q

What hormones are produced in the kidneys?

A

Erythropoietin (EPO)
Renin-Aldosterone-Angiotensin System
1, 25-dihydroxyvitamin D3

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2
Q

What is the site of synthesis for EPO?

A

Kidney

Fetus-Liver

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3
Q

What is the function of EPO?

A

Stimulate development of RBC’s

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4
Q

What controls the secretion of EPO?

A

Endorphins
Substance P
Oxytocin
Thyroxine

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5
Q

The renin angiotensin aldosterone system regulates?

A

BP

Fluid Balance

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6
Q

The renin-angiotensin-aldosterone system is activated if there is a loss of?

A

Blood Volume

BP

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7
Q

What signals the juxtaglomerular cells to release renin?

A

Macula Densa Cells

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8
Q

Macula densa senses a decrease in blood pressure which causes a decrease in?

A

Glomerular Filtration Rate (GFR)

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9
Q

What is the function of macula densa cells?

A

Stimulates renin release in juxtaglomerular cells

Osmolarity of plasma

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10
Q

What cells in the kidney release renin into circulation?

A

Juxtaglomerular Cells

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11
Q

What causes blood vessels to constrict?

A

Angiotensin II

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12
Q

Angiotensin II stimulates the release of aldosterone from the?

A

Adrenal Cortex

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13
Q

Aldosterone increases reabsorption of sodium and water which increases?

A

BP

Fluid Volume

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14
Q

The renin-angiotensin-aldosterone system stimulates the release of?

A

Norepinepherine

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15
Q

Renin-angiotensin-aldosterone system increases vasoconstriction of blood vessels which increases BP when the pressure is too?

A

Low

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16
Q

The kidney and it’s hormones brings BP up to?

17
Q

What hormone regulates the amount of water excreted by the kidneys?

A

Antidiuretic Hormone (ADH)

18
Q

What monitors either the amount of volume of blood going through the hypothalamus or the concentration of water in the blood?

19
Q

Aldosterone is secreted from what part of the adrenal gland?

A

Zona Glomerulosa

20
Q

What is the primary target of aldosterone?

21
Q

Aldosterone is important for what?

A

Sodium and Water Absorption

22
Q

PTH regulates what?

A

Calcium and Phosphate

23
Q

What is the site of synthesis for atrial natriuretic peptide?

A

Atrium of the heart

24
Q

ANP stimulates renal excretion of sodium by decreasing secretion of?

A

Angiotensin II

25
What's the primary function of ADH?
Increase Renal Reabsorption of Water
26
What disease has a decreased output of ADH?
Central Diabetes Insipidus
27
Central diabetes insipidus has what symptoms?
Excessive Urine Output and Thirst
28
Central diabetes insipidus has increased aldosterone after?
Compensation
29
What is the reason for increased aldosterone after compensation?
BP drops and body tries to restore it to normal
30
What are the physical characteristics of central diabetes insipidus?
Polyuria Dilute Urine Hypotension Increased Plasma Concentration
31
What disease has a decreased sensitivity to ADH but and increased secretion of ADH?
Nephrogenic Diabetes Insipidus
32
Excessive release of ADH causes what disease?
Syndrome of Inappropriate ADH secretion
33
Syndrome of inappropriate ADH secretion causes fluid overload in patients which can lead to?
Strokes Head Trauma Brian Tumors