kinetics and dynamics

Question 1

what the drug does to the body

Answer 1

pharmacodynamics

Question 2

what the body does to the drug

Answer 2

pharmacokinetics

Question 3

what happens to the drug from the time it is introduced to the body until it reaches the circulating fluids and tissues

Answer 3

absorption

Question 4

the way the drug moves through the bloodstream to its target organs

Answer 4

distribution

Question 5

breakdown of drugs

Answer 5

metabolism

Question 6

kidneys remove drug byproducts from the body

Answer 6

elimination

Question 7

the time it takes for half of medication to be eliminated in body

Answer 7

half-life

Question 8

the activation of drugs in liver and intestines

Answer 8

first pass effect

Question 9

mimic ligand-receptor activation response

Answer 9

agonist

Question 10

block the receptors activation response

Answer 10

antagonist

Question 11

how a medication functions within the body

Answer 11

mechanism of action

Question 12

cheaper, no capital letter, same chemical ingredient (may have different talc/ flavoring)

Answer 12

generic name

Question 13

name given, time-limited patent, capital letter

Answer 13

brand name

Question 14

time it takes when it firsts starts working

Answer 14

onset

Question 15

highest level effect

Answer 15

peak

Question 16

how long it works

Answer 16

duration

Question 17

how can grapefruit interact with medications

Answer 17

certain foods interact with drugs, many have warnings, grapefruit juice can increase dose

Question 18

lowest level of the drug in the patients body

Answer 18

trough

Question 19

what is the pharmacokinetic processes (ADME)

Answer 19

absorption, distribution, metabolism, elimination

Question 20

what are some routes for absorption

Answer 20

oral, subcutaneous, intramuscular, intravenous, ng tube, inhalers

Question 21

types of parenteral injections

Answer 21

subcutaneous, intramuscular, intravenous

Question 22

protein binding is

Answer 22

tightly bound drugs are released slowly and have longer duration, loosely bound drugs act faster and are excreted quicker

Question 23

blood-brain barrier

Answer 23

protects brain and keeps harmful substances away from brain including many drugs (highly lipid-soluble more likely to pass than non lipid-soluble)

Question 24

what is the most important site for metabolism

Answer 24

liver

Question 25

removal of drugs from the body (can include sweat, saliva, bile, breast milk, and feces)

Answer 25

excretion

Question 26

areas on cell membrane that react to certain drugs to cause an effect within the cell

Answer 26

receptor sites

Question 27

list some factors that can influence drugs and effectiveness

Answer 27

weight, age, gender, physiological, pathological, genetics, immunological, psychological, environmental, tolerance, accumulation, interactions

Question 28

drug-drug interaction

Answer 28

occur any time two or more drugs are taken together

Question 29

amount of drug required to produce therapeutic response leading to potentcy

Answer 29

dose-response relationship

Question 30

therapeutic response

Answer 30

intended response

Question 31

side effects or adverse effects

Answer 31

anticipated effects other than intended

Question 32

serious adverse effects

Answer 32

unintended effect that causes harm, often requires discontinuation of drug