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Pharmacokinetics > Kinetics BrainScrape CYPs > Flashcards

Kinetics BrainScrape CYPs Flashcards

(77 cards)

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1
Q

Amiodarone

A

Inhibitor of CYP2C9

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2
Q

Azoantifungals

A

Substrate CYP3A4

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2
Q

Barbiturates

A

Inducer of CYP2C19

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3
Q

Benzos except lorazepam/oxazepam

A

Substrate CYP3A4

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3
Q

Carbamazepine

A

Inducer of CYP 3A4

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3
Q

Caffeine

A

Substrate of CYP1A2

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3
Q

Carbamazepine

A

Inducer of CYP2C9

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4
Q

CCBs

A

Substrate CYP3A4

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5
Q

Charbroiled meat

A

Inducer of CYP1A2

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6
Q

Chlorpromazine (antipsychotics)

A

Substrate of CYP2D6

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8
Q

Chlorzoaxazone

A

Substrate of CYP2E1

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9
Q

Clarithromycin

A

Inhibitor of CYP3A4

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9
Q

Cimetidine

A

Inhibitor of CYP3A4, 1A2, 2C9

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9
Q

Clozapine

A

Substrate of CYP1A2

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9
Q

Cigarette smoke

A

Inducer of CYP1A2, CYP2E1

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9
Q

Cipro

A

Inhibitor of CYP1A2

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9
Q

Bisoprolol

A

Substrate of CYP2D6

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11
Q

Codeine (opioid analgesics)

A

Substrate of CYP2D6

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12
Q

Cruciferous vegetables

A

Inducer of CYP1A2

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13
Q

Dexamthasone

A

Inducer of CYP 3A4, 2C9

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13
Q

Diazepam

A

Substrate of CYP2C19

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14
Q

Diltiazem

A

Inhibitor of CYP1A2

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15
Q

Disulfram

A

Inhibitor of CYP2E1

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16
Q

Ecainide (antiarrhthmics)

A

Substrate of CYP2D6

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17
Efavirenz
Inducer of CYP 3A4
17
Enflurance
Substrate of CYP2E1
18
Enoxacin
Inhibitor of CYP1A2
19
Erythryomycin
Inhibitor of CYP3A4
20
Ethanol
Inducer and Substrate of CYP2E1
21
Fluoxetime (most SSRIs)
Substrate of CYP2D6
21
Fluconazole
Inhibitor of CYP2C9
22
Fluoxetine
Inhibitor of CYP2D6, 2C19
22
Fluvastatin
Substrate of CYP2C9
24
Fluvoxamine
Most potent Inhibitor of CYP1A2, also inhibitor of CYP2C9, 2C19
25
Garlic
Inhibitor of CYP2E1
26
Glibenclamide
Substrate of CYP2C9
28
Glimipiride
Substrate of CYP2C9
29
Glipizide
Substrate of CYP2C9
30
Grapefruit Juice
Inhibitor of CYP3A4
31
Halothane
Substrate of CYP2E1
32
HMG-CoA Reductase Inhibitor except Pravastatin
Substrate CYP3A4
34
Isoflurane
Substrate of CYP2E1
35
Isoniazid
Substrate of CYP2E1
37
Itraconazole
Inhibitor of CYP2C9
37
Isoniazid
Inducer of CYP2E1
38
Ketoconazole
Inhibitor of CYP3A4
39
Macrolide antibiotics except Azithromycin
Substrate CYP3A4
41
Methoxyflurane
Substrate of CYP2E1
42
Metronidazole
Inhibitor of CYP2C9
43
Nevirapine
Inducer of CYP 3A4
44
Norfloxacin
Inhibitor of CYP1A2
45
NSAIDs
Substrate of CYP2C9
46
Olanzapine
Substrate of CYP1A2
48
Omeprazole
Substrate of CYP2C19 and Inhibitor of CYP2C19 inducer of CYP1A2
50
Paroxetine
Inhibitor of CYP2D6
51
Phenobarb
Inducer of CYP3A4, 1A2, 2C9,
52
Phenytoin
Inducer of CYP3A4, 2C9,
54
Primidone
Inducer of CYP 3A4, 1A2,
54
Quinidine
Inhibitor of CYP2D6
56
R-warfarin
Substrate of CYP1A2
58
Rifabutin
Inducer of CYP 3A4
60
Rifampin
Inducer of CYP 3A4, 1A2, 2C9, 2C19
61
Riluzole
Substrate of CYP1A2
62
Ritonavir
Inhibitor of CYP3A4, 1A2, 2E1
64
Ropivacaine
Substrate of CYP1A2
66
S-mephenytoin
Substrate of CYP2C19
67
S-warfarin
Substrate of CYP2C9
68
Sevoflurane
Substrate of CYP2E1
69
SJW
Inducer of CYP3A4, 2E1, 2C9
70
Steroids (BC, corticosteroids)
Substrate CYP3A4
71
Sulfonamides
Inhibitor of CYP2C9
72
Tacrine
Substrate of CYP1A2
73
Theophylline
Substrate of CYP1A2
74
Tolbutamide
Substrate of CYP2C9
75
Tricyclic antidepressants
Substrate of CYP2D6
76
Troleandomycin
Inhibitor of CYP3A4
77
zileuton
Inhibitor of CYP1A2

Pharmacokinetics (1 decks)

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