L1: INTRO (Immunology)

Question 1

Developed a vaccine against smallpox

Answer 1

Edward Jenner

Question 2

First to demonstrate phagocytosis

Answer 2

Ernst Haeckel

Question 3

Live, attenuated chicken cholera and anthrax vaccines

Answer 3

Louis Pasteur

Question 4

Cellular theory of immunity through phagocytosis

Answer 4

Elie Metchnikoff

Question 5

First report of live “attenuated” vaccine for rabies

Answer 5

Louis Pasteur

Question 6

Therapeutic vaccination

Answer 6

Louis Pasteur

Question 7

Humoral theory of immunity

Answer 7

Emil von Behring

Question 8

Demonstration of cutaneous (delayed-type) hypersensitivity

Answer 8

Robert Koch

Question 9

Antibody formation theory

Answer 9

Paul Ehrlich

Question 10

Immediate-hypersensitivity anaphylaxis

Answer 10

Paul Jules Portier, Charles Richet

Question 11

the most widely used indicator of acute inflammation.

Answer 11

C-reactive Protein

Question 12

has high affinity for HDL cholesterol and is transported by HDL to the site of infection

Answer 12

Serum Amyloid A

Question 13

refers to a series of serum proteins that are normally present and whose overall function is mediation of inflammation.

Answer 13

Complement

Question 14

binds irreversibly to free hemoglobin released by intravascular hemolysis.

Answer 14

Haptoglobin

Question 15

acts as an antioxidant to provide protection against oxidative damage mediated by free hemoglobin

Answer 15

Haptoglobin

Question 16

clot increases the strength of a wound and stimulates endothelial cell adhesion and proliferation, which are critical to the healing process

Answer 16

Fibrinogen

Question 17

creates a barrier that helps prevent the spread of microorganisms further into the body.

Answer 17

Fibrinogen

Question 18

• makes blood more viscous and serves to promote aggregation of red
  blood cells (RBCs) and platelets.

Answer 18

Fibrinogen

Question 19

• a copper-transporting protein in human plasma

Answer 19

Ceruloplasmin

Question 20

• a depletion of ceruloplasmin is found in ___ , an autosomal
  recessive genetic disorder characterized by a massive increase of copper
  in the tissues.

Answer 20

Wilson’s disease