L1 Intro to Endo

Question 1

What is the endocrine system?

Answer 1

System of ductless glands which secrete chemical messenger into blood

Question 2

What is the role of the thyroid and parathyroid glands?

Answer 2

control of metabolic rate and calcium homeostasis

Question 3

What are the 3 types of receptors involved in hormone action?

Answer 3

• Steroid Hormone Receptors
• G-Protein Coupled Receptors
• Tyrosine Kinase Receptors

Question 4

Describe steroid hormone receptors

Answer 4

stimulates gene expression

Question 5

Describe the GPCR

Answer 5

7TM

causes synthesis of second messenger (IP3, cAMP)

Question 6

What are the 2 types of hormones?

Answer 6

peptide hormones
steroid hormones (+thyroid hormone)

Question 7

Describe peptide hormones

Answer 7

Chains of amino acids, highly water soluble, susceptible to protease attack.
Unable to cross the cell membrane without a carrier protein, act on membrane-bound receptors.

Question 8

Describe steroid hormones

Answer 8

Highly lipid soluble, poorly water soluble, must be transported in blood bound to plasma protein. Only unbound hormone biologically active. Able to cross the cell membrane and act on intracellular receptors