L1 - L6

Question 1

Breast Cancer Hormonal Therapies

• ER antagonist
• Tamoxifen

Answer 1

Tamoxifen
- prevents BC and BC recurrence

• early stage 2 tumours extremely
• preferred drug for pre-meno

S/E - inc. risk of uterine cancer & blood clots

Question 2

Chemo Drugs

• PLATINATES (“alkylating like”)
• cisplatin + carboplatin

Answer 2

S/E:

• neurotoxic, nephrotoxic (dose-limiting), myelotoxic

Question 3

Chemo Drugs

• ANTHRACYCLINE (Doxyrubicin)

Answer 3

S/E: Nausea/vomiting, extravasive, myelosuppression, infertility, dehydration.

cardiotoxic - never give to CVD patients

Question 4

SACT Supportive Meds

Answer 4

metoclopramide - antiemetic, dopamine receptor antagonist

ondansetron - antiemetic, serotonin receptor antagonist

Loperamide - diarrhoea

Gabapentin - for neuropathies (nerve damage)

Filgrastin GCSF
- especially in ppl with low neutrophils from chemo
- treats neutropoenia

Question 5

regular blood checks vital

Answer 5

done in the hospital