L11 Disease caused by infection

Question 1

What is a pathogen?

pathogenic microorganisms

Answer 1

infectious agents that cause disease and damage tissue

Question 2

Infection

Answer 2

successful persistence/multiplication of pathogen on/within the host

Question 3

Virus

Answer 3

incapable of replicating themselves without a host cell
no machinery
Genome RNA or DNA
composed of nucleus, capsid, -/+ lipid membrane
icosahedral/helical lipid envelope

classified by tropism: type of cell/tissue they infect and pathology: where they cause the disease

Question 4

Bacteria

Answer 4

can replicate in or outside cell 
can make own nucleic acids and proteins 
prokaryotes 
single celled organism 
Capsules, flagella, pilli 
shape-rod, coccus, spiral

Question 5

Fungi

Answer 5

Eukaryotes
grow as rounded yeast cells or slender filamentous hyphae
superficial infection

Question 6

Protozoa

Parasite

Answer 6

single celled eukaryotes

Question 7

Helminths

Parasite

Answer 7

parasitic worms

complex life cycles

Question 8

Prions

Answer 8

Transmission protein

misfolded form of normal cellular prion protein

Question 9

Pathogenicity

Answer 9

Pathogenicity is the capacity to cause disease
is determined by
Virulence factors-determines how severe the disease is