L13: Bacterial Diversity & Archaea Flashcards
(221 cards)
our knowledge of microbes is limited because…
many bacteria have not been formally identified
many bacteria have not been formally identified for 2 main reasons:
they have not been cultured (yet)
they are part of complex food chains requiring other bacterial products (syntrophy - cross-feeding)
PCR indicates that there about __________ bacterial species per g of soil
10,000
most bacteria in humans is in what size range?
small to average
what are the shared characteristics of archaea and eukarya?
CELL WALLS: varies in composition, but NO peptidoglycan
START AA: Methionine
NO rRNA Loop
what are the shared characteristics of bacteria and eukarya?
MEMBRANE LIPIDS: straight C chains attached to glyercol
has tRNA
unique characteristics of archaea?
varies in antibiotic sensitivity
lacks tRNA
why do archaea vary in antibiotic sensitivity?
some antibiotics that target bacterial ribosomes can affect archaeal ribosomes
unique characteristics of bacteria?
peptidoglycan cell walls
first AA is Formylmethionine
has clear antibiotic sensitivity
why are bacteria sensitive to antibiotics?
antibiotics often target peptidoglycan and other unique structures that cause great damage
unique characteristics of eukarya?
has no antibiotic sensitivity
archaea have distinct ______________
taxonomic grouping
archaea are 2 things; what are they?
extremophiles and methanogens
2 types of extremophiles
halophiles
thermophiles
halophiles
tolerate or thrive in high-salt environments; requires salt concentration >25%
thermophiles
tolerate or thrive in high-heat environments; requires growth temp >80 degrees C
methanogens
obligate anaerobes
produce methane
performs pathogenesis
examples of archaea as methanogens
methanogenic archaea in the gut and other bodily sites
the teeth - usually, archaeal presence means a dental disease
what is obscure about methanogens?
no clear role in pathogenesis
role in human health is still being studied
why can archaea live in the human body at all?
some portions of the body naturally exist at a level or can become anaerobic enough for archaea to grow (usually signifies disease)
how do certain bodily bacteria stay within their designated regions?
limitations based on the immune system or properties of that bacteria that prevent them from spreading
opportunistic pathogen
specifically targets weakened, immunocompromised individuals
primary pathogen
targets everyone, including the healthy
BACTERIAL CHARACTERISTICS: peptidoglycan cell walls
comprises Ester-linked lipids, which are mostly phospholipids and glycerol diesters of fatty acids