L23

Question 1

What are the 2 types of PG drugs?

Answer 1

Steroidal anti-inflammatory and non-steroidal anti-inflammatory

Question 2

What do corticosteroids act on?

Answer 2

Preventing release of Arachidonic Acid via inhibition of PLA2

Question 3

Which part of the pathway do NSAIDs act on?

Answer 3

COX

Question 4

What are NSAIDs commonly referred to as?

Answer 4

analgesic antipyretic drugs

Question 5

Which COX inhibitors have more cardio a hazards?

Answer 5

COX-2 inhibitors

Question 6

What is the most effective analgesic?

Answer 6

Ketorolac

Question 7

What is the main use of aspirin?

Answer 7

Prophylaxis against thrombotic event in patients of cardiovascular diseases

Question 8

When is the best time to take NSAIDs?

Answer 8

With meals

Question 9

What are NSAIDs commonly available as to the public?

Answer 9

Topical formulations

Question 10

How do selective COX inhibitors differ from NSAIDs, in terms of side effects?

Answer 10

Less gastric injury

Question 11

Does paracetamol belong to the NSAID group?

Answer 11

No.

Question 12

Why does paracetamol not belong to NSAID group?

Answer 12

Lacks the inflammatory effect

Question 13

Is paracetamol safe for children and pregnant women?

Answer 13

Yes.

Question 14

Why is a large dose of paracetamol fatal?

Answer 14

Due to it causing hepatic toxicity

Question 15

what drug acts on the LOX pathway?

Answer 15

Zileuton

Question 16

What drug acts on Leukotrienes?

Answer 16

Montelukast