L26-27 DNA and RNA viruses

Question 1

which viral infection causes oral sqamous papilloma / squamous cell carcinoma (verrucous carcinoma ?

Answer 1

papovaviruses

Question 2

what is the shape of papovaviruses ?

Answer 2

icosahedral

Question 3

how are papovaviruses transmitted ?

Answer 3

through direct contact or autoinoculation

Question 4

how are adenoviruses spread?

Answer 4

respiratory and ocular secretions

Question 5

what does an adenovirus infection cause ?

Answer 5

acute respiratory disease , pharyngitis , and conjunctivitis

Question 6

herpes family of viruses include :

Answer 6

herpes simplex 1 and 2
varicella zoster virus
epstein barr virus
cytomegalo virus
human herpes virus 6,7,8

Question 7

what does a herpes simplex 1 viral infection cause ?

Answer 7

acute gingivastomatitis : painful vascular lesions on gums , lips , and oral mucosa

herpatic kertoconjuctivitis

encephalitis

herpatic witlow

Question 8

herpes simplex 2 infection causes:

Answer 8

genital herpes

aseptic meningitis

neonatal herpes

Question 9

what does varicella-zoster infection result in ?

Answer 9

varicella (chickenpox) : primary infection usually in childhood)
zoster ( shingles) : reactivation of earlier varicella

Question 10

how is a zoster infection different from varicella ?

Answer 10

shingles rash is similar to varicella but it is limited to skin innervated by a dorsal root ganglia (usually trigeminal)

Question 11

what smear is used in order to see multinucleated giant cells in varicella-zoster infection?

Answer 11

tzank smear

Question 12

PCR in screening for varicella-zoster virus looks for viral DNA in the ____

Answer 12

CSF

Question 13

Which viral infection is characterized by lymphocytosis ?

Answer 13

Epstein barr virus

Question 14

which viral infection is associated with human malignancies such as Burkits lymphoma , nasopharengeal carcinoma and oral hairy leukoplakia ?

Answer 14

Epstein barr virus

Question 15

the latent form of epstein barr virus is present within ____

Answer 15

lymphocytes , B cells

Question 16

high risk groups for symptomatic cytomegalovirus infection:

Answer 16

HIV / AIDS patients

organ transplant recipients

fatal to newborns if acquired congenitally

Question 17

which viral infection has an owl eye apperance under the microscope?

Answer 17

cytomegalovirus

Question 18

which lymphocytes does human herpes virus 6 have affinity to?

Answer 18

both B and T cells

Question 19

which viral presence is usually asymptomatic in healthy adults ?

Answer 19

cytomegalovirus

Question 20

what diseases can be cause by human herpes virus 6?

Answer 20

mononucleosis with cervical lymphadenopathy

exanthem subitum (roseola infantum )

Question 21

human herpes virus 6 is present in :

Answer 21

saliva of most healthy adults

Question 22

what is HHV-7 associated with ?

Answer 22

rashes

Question 23

which lymphocytes are affected by HHV-7 ?

Answer 23

T cells

Question 24

which virus is associated with kaposis sarcoma ?

Answer 24

HHV-8
Also associated with vascular endothelial tumor which is common in HIV patients

Question 25

which group of viruses is responsible for influenza infection ?

Answer 25

orthomyxovirus

Question 26

orthomyxoviruses are subdivided into types A, B , and C based on :

Answer 26

nucleocapsid protein NP and viral envelope matrix protein :protein M

Question 27

nomenclature of influenza viruses is based on :

Answer 27

hemogglutanin (H) and neuriminidase (N)

Question 28

which viruses have a spherical structure and segmented , 8 piece ssRNA (capable of genetic re-assortment ?

Answer 28

orthomyxoviruses

Question 29

which group of viruses includes mumps , measles and parainfulenza , RESPARITORY syncytial virus ?

Answer 29

paramyxoviruses

Question 30

describe the structure of paramyxoviruses :

Answer 30

pleomorphic Single linear ssRNA

Question 31

influenza virus possesses: nucleocaspid shape: transmission :

Answer 31

RNA polymerase helical respairatory aerosols

Question 32

what is the difference between antigen shift and antigen drift?

Answer 32

antigen shift is a major re-assortment of RNA segments while Antigen drift is a minor change or mutation in the RNA

Question 33

what diseases are caused by resparatory syncytial virus ?

Answer 33

pneumonia and bronchitis in infants otitis media in children

Question 33

what diseases are caused by resparatory syncytial virus ?

Answer 33

pneumonia and bronchitis in infants otitis media in children

Question 34

what are the complications of mumps viral infection ?

Answer 34

paratitis in one of or both parotid glands

Question 35

attenuated form of which virus is used in the measles mumps rubella vaccine ?

Answer 35

mumps virus

Question 36

what are the complications of measles ?

Answer 36

respiratory issues neurological issues gangrenous stomatitis and noma --> can lead to destruction of orofacial tissue and consequent disfigurement when paired with necrotizing ulcerative gingivitis , malnutrition and oral ulcers rash

Question 37

rna virus = helical dna virus = sphere papillovirus : unenveloped herpes: enveloped orthomyxovirus : sphere corona virus : enveloped

Answer 37

.

Question 38

group A coxsackie viruses cause:

Answer 38

herpangia : herpes like oropharengitis hand food , and mouth disease

Question 39

what is the receptor for SARS coronavirus on the surface of cells ?

Answer 39

angiotensin converting enzyme 2

Question 40

pneumonia caused by SARS is charecterized by

Answer 40

diffuse edema resulting in hypoxia

Question 41

MERS is caused by MERS-CoV : BINDS TO cd26