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B.3 > L.34 Enteral dosage form > Flashcards

L.34 Enteral dosage form Flashcards

(68 cards)

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1
Q

pharmaceutical dosage form butuh additive material ber pH

A

additive materal yang netral

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2
Q

benefits pharmaceutical dosage form untuk ingradeint dan palate

A

melindungi ingrediant, menutupi rasa pahit

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3
Q

enteral dosage from ada 2 bentuk dari tempat masuknya

A

oral, rectal

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4
Q

oral ada

A

sulingual, , , ,

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5
Q

physical form of dosage form

A

solid, liquid

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6
Q

solid ada

A

powder/pulveres
tablet (compress, coated, slow release)
kapsul
suppositories

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7
Q

liquid form ada

A

…

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8
Q

kaplet

A

tablet berbentuk kapsul

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9
Q

effervescent

A

kapsul yang sssssss sss

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10
Q

powder advantage

A

bisa untuk anak dan ortu yang tidak bisa nelen

lebih mudah menyesuaikan dosis

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11
Q

powder disanvantage

A

tidak stabil dalam air
rasa pahit dan bau
harus diminum pakai air putih

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12
Q

powder ciri

A

rapid onset
limited…?
large surfa area?

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13
Q

tablet kompress ciri

A

chewavle, efefrvescent, sulingual, buccal, lozenges, odt

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14
Q

coating tablet jenis

A

sugar coated, enteric? coated, film coated

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15
Q

ciri compressed tablet

A

oval/ flat round
poorly absorbed
difficult to swalloe
di dalemnya ada lebih dari 2 medicine?

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16
Q

chewable tablet

A 
quickly absorbed
good taste
local effect: antacid
systemic: antibiotics, vitamin
not suitable for ppl with no teeth
suitable for mobile ppl
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17
Q

effervescent tablet

A

systemic effect

contain effervescent salt

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18
Q

buccal tablet

A

absorption via buccal mucosa

bypass 1st pass metabolism

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19
Q

buccal tablet adv

A

rapid,

high bioavailaility

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20
Q

buccal disan

A

tidak nyaman di mulut

hanya bisa deliver small dosage

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21
Q

sublingual tablet

A

under tongue
bypass 1 pass metab
ISSD for heart

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22
Q

sublingual tablet adv

A

rapid onset, 5 min

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23
Q

lozenger/trochess ciri

A

efek hanya lokal (anaesthetic / antibiotik lokal)
praktis
yng populer punya funky shape

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24
Q

Orally disintegrating tablet ciri

A

small, easily broken filler

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25
Orally disintegrating tablet adv
highly soluble ga butuh air anyak cocok buat pediatric n geriatric, impaired swallowing, ginjal impairment contoh: zinkid
26
sugarcoated tablet/ dragee
untuk protection agains airborne, moisture, sunlight particle umpleasant taste slow release?
27
film coated tablet
compressed tablet coated with think insoluble polymer | untuk?
28
enteric coated tablet
tidak hancur di lambung tp ancur di usus karena iritasi lambung (aspirin protects the drug dari asam lambung (erythromycin)
29
enteric coated jangan
tidak diberikan separuh ya!! harus terbungkus utuh, gabole dipecaha atu dikunyah
30
slow release tablet
slow and susained release over a period of time agar konsentrasi di darah konstan consist of 2/3 layer, rilis tiap layer dikit" tiap 12-8 jam
31
slow release tablet adv
sustained concentration dan actuin frekuensi konsumsi turun efektif, side effect turun
32
slow release talet disan
mahal dosis tidak bisa fleksibel, gaisa dipersonalized manufacturing failure -> overdosis!
33
slow release talet
jangan dikunyah atau dipecah dosis udah berlipat
34
soft capsule
``` elastic shell (gelatin with alcohol/glyverin and sorbitol) penyimpanan lama-lama jadi keras ```
35
hard capsule
higroskopis, lama-lama lunak | isi powder granule
36
hard capsule adv
mask taste and color dissolve in gastric juice tasteless
37
hard capsule disad
difficult to swallow | mudah lunak kalau penyimpanan lembab
38
ss garfik kapsul
kapsul, tablet, slow release kapsul, slow release tablet
39
suppositories
buat delivery ke body orifices where they soften/dissolved
40
rectal suppositories
systemic, local effect | act rapidly, no 1st pass metab
41
vaginal suppositories
local only
42
rectal suppositories disad
uncertain absorption, local irritation
43
rectal suppositories kalo
pasien unconscious, muntah", uncooperative, kejang (IV akal susah)
44
perhatikan apa sebelum mau kasiin liquid dosage form?
beepbeep?
45
solution
jernih (faster asorption, homogen) | bisa dengan atau tanpa pemanis/perasa/warna
46
solution adv
suitable for kids
47
solution disad
large volume required
48
suspensi
turbid, drug thats not solubele | with suspensor
49
suspensi disad
absorption
50
emulsion
oil in water or vice versa turbid sweeteer/ falvaor with or withour
51
emulsion -
air sama oil misah kalau udah lama
52
medicated syrup
concentrated | mengandung sugar/its sustitute
53
medicated syrup +
asorbsi lbh cepet dr solid pleasant taste suitale for kids
54
medicated syrup -
inaccuracy dosage
55
dry syrup
unstable kalo di liquid form liquid form 7 hari di room temp, 14 hari di refri harus dikasih akuades dulu
56
elixir
10-17 % alkohol sg pengawet, pelarut bahan aktif | palatable, tidak begitu kental
57
elixir advantage
insolubke drug masuk ke hydroalcohol | less viscous
58
elixir -
?
59
oral drop
cocok untuk ayi | manis
60
garfik penyerapan bentuk
..
61
theophylline dan entuk konsentarsi
..
62
journey menuju bzlood
..
63
klasifikasi perizinan obat
..
64
question 1
anticonvulsant: rectal antipyretics: drop, syrup, enteric coated (kalo obatnya dikasih setahunan)
65
q2
solution
66
q3
elixir sama dgn solution | syrup bisa suspension jd tergnatng bentuknya
67
q4
sugar coated tablet
68
kaplet dan kapsul, lebih lama mana?
kaplet. kapsul kan isinya powder, begitu luarnya benyek udah bisa cepet diserap

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