L37 STiner jones adaptive immune response

Question 1

Native T cells display which ligan

Answer 1

L selecting

Question 2

Activated T cells display which ligands

Answer 2

E, P selectin

ICAM-1 VCAM-1

Question 3

Responses of activated macrophages

Answer 3

Kill phagocytosed micrboes (ROI, NO)
Secrete TNF, IL-1, chemokines, IL-12
Increase MHC and B7 expression

Question 4

CTL target recognition molecules

Answer 4

MHCI
CD8
LFA-1

Question 5

CTL mediated lysis of target cell

Answer 5

Antigen recognition and conjugate formation of LFA-1 and ICAM-1
CTL activation
Granule exocytosis
Detachment of CTL
Target cell death

Question 6

Mutations in Fas cause

Answer 6

Autoimmune disease

Question 7

Immune response to extracellular pathogens is initiated by

Answer 7

Macrophages and neutrophils

Question 8

Driver of cell mediated immunity

Answer 8

Th1

Question 9

Soluble antigen capable of activating B cell is usually

Answer 9

antigen w/ long repeating epitopes but not proteins

Question 10

IgA must be secreted onto

Answer 10

Mucosal surfaces