L4 - pulmonary circ Flashcards

(28 cards)

1
Q

functions of pulmonary circ (PULMC)

A

gas exchange
-reservoirs for blood
filter
synthesis and metabolism

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2
Q

structure of pulm vessels

A

thin walled and highly branched than systematic vessels

-

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3
Q

why is the pressure lower in PULMC than SYSTMC

A

the pulm vessels are wider and shorter so the blood move slower
- it has a lower resistance

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4
Q

does pulmc receives all of right ventricular output

A

yes

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5
Q

what features are low in pulmc

A

pressure due to thin wall and resistance due to short vessles and larger raduis

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6
Q

other features of pulmc

A

vessels can change shape easily

  • have large SA capillary
  • returns blood to left ventricle
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7
Q

whats the value of pulm ABP at the pulm artery value

A

28/8 mmHg

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8
Q

whats the pulm capillary pressure at pulmon artery level

A

8~10mmHg

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9
Q

difference in distance and its pressure between heart level to apex and base seperately

A

15cm and 12 mmHg for both distances

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10
Q

whats the pressure near base of the lungs when standing upright

A

28/8+12/12= 40/20 mmHg.

- the pressure becomes greater so the vessels becomes distended

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11
Q

whats the pressure near apex of the lungs when standing upright

A

28/8-12/12= 16/-4

  • pressure not high enough so the vessels collapse
  • no perfusion
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12
Q

when standing upright, what happends to pulm perfusion

A

increases from apex to base

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13
Q

when lying, what happens to pulm

A

perfusion is evely distributed from apex to base

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14
Q

what is capacitance of the pulm blood vol

A

when lying, there’s greater blood vol so higher capacitance

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15
Q

capacitiance functions

A
  • standing upright increases return to left chambers
  • CO and pulm ABP increases, perfusion increases
  • increases blood vol
  • if left ventr failure happens, filling towards the apex occurs
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16
Q

vasocont influences on pulmc

A

increased SNS activity increases pressure in pulmc and perfusion

  • inflamm mediators like histamine
  • hypoxia - pulm vasocon
17
Q

what is hypoxia

A

when O2 supply not enough and not being supplied

18
Q

what happens when theres hypoxia in one of the capillary

A

-vasocon of that capillary occurs
-this diverts the blood flow to other capillaries
=improves O2 exchanged

19
Q

what happens if the hypoxia occurs throughout the lungs

A
  • generalised pulm vasocon
  • increases intravascular pressure
  • limits O2 supply
20
Q

effects of generalised pulm vasocon (chronic hypoxia)

A
  • increases resistance in pulmc
  • widens vascular SM so increases vasc R
  • increases capillary hydrostatic pressure so more filteration out of capillaries > pulm odema
  • impaired gas exchange
21
Q

what happends during filteration across the pulm capillaries

A
  • net outward filteration due to capillary HP higher than tissue HP
  • tissue OP is higher in pulmc than sysmc so smaller OP pulls filteration into capillaries
  • excess fluid taken away from lymph
22
Q

what happends during filteration in the capillaries in lungs when the pulm CAP increases

23
Q

what occurence it can lead to in the capillaries in lungs when the pulm CAP increases too much

A

alveolar odema which is not good as the alveoli need to be kept dry

24
Q

what occurences does pulm odema occur in

A

hypoxia, inflammation, extreme exercises, anaphyliatic responses, left ventricular failure

25
what is microthrombi
- small particles of blood cells and fibrin together aggregrate - get stuck in pulm ciric
26
what is pulm embolism
blood clot, air or fat that block pulm vessels
27
what do pulm cells syntheisise
NO to cause Pulm vasodil in response to stress -PGI2- cause dilation ACE
28
what do pulm endothelial cells remove
serotonin (5-HT) and NAdr