L6 Hypersensitivity Flashcards

1
Q

Immune responses that cause tissue injury are called?

diseases caused by these are called?

what do they arise from?

what classes?

A
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2
Q

Mechanisms of Hypersensitivity

Types?

description?

A
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3
Q

Type 1 hypersensitivity

what is it and what is it caused by?

triggered by what type of Ag?

if someone is Atopic what does that mean?

A
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4
Q

hypersensitivity type I

Mast cell mediators?

the most important ones?

Their roles?

A
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5
Q

Initial allergen encounter

start to binding of mast cell

A
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6
Q

Subsequent allergen encounters

A
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7
Q

Type I

sequence of events

A
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8
Q

The phases through the Type I response

what they cause?

timing?

A
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9
Q

Type 1 disease

Local reaction

what is it?

caused by?

What mechanism?

what else can cause it?

A
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10
Q

Type 1 disease

Systemic reaction

what cause this?

results in?

A
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11
Q

Allergen testing

What type does it test for?

often performed where?

what is a positive reactions?

A
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12
Q

Allergen-SIT?

What do you do?

what does it cause?

What else plays a role?

A
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13
Q

Type II hypersensitivity?

What cells play a role?

A
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14
Q

Diseases of Type II hypersensitivity?

A
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15
Q

Different effector mechanisms of Type II

A
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16
Q

Effector mechansims Type II

A.

B.

C.

17
Q

Type III hypersensitivity

what are they?

induce what?

major mechanism?

18
Q

Diseases of Type III hypersensitivity

Human diseases caused by what?

injury caused by?

19
Q

Effector mechanisms Type III

20
Q

Type IV hypersensitivity

Major triggers?

Tissue injury by?

21
Q

Diseases of Type IV hypersensitivity?

what plays dominant role in causing tissue injury?

Autoimmune diseases mediated by type IV?

Inflammatory diseases?

22
Q

Type IV hypersenstivity

called what?

caused by what?

tissue injury by what?

chronic or acute?

autoimmune diseases caused by?

also cause this?

23
Q

Delayed-type Hypersensitivity?

time?

PPD?

DTH reaction senstive?

24
Q

Contact dermititis

Poison ivy

25
Allergic contact dermititis What type of exposure? type of hypersensitivity? most common contact allergen?
26
Granulomatous inflammation? What is it? What cell types? creation of granulomas how?
27
what a mature granuloma looks like?
28
Mature granuloma formation Time? formation how?
29
Systemic Lupus Erythematosus Type of Hypersensitivity? clinical manifestation? Auto-Abs? which cause? Diagnostic test?
30
Rheumatoid ARthristis Type of hypersensitivity? cells involved? diagnostic test?
31
Multiple Sclerosis Type of hypersensitivity? what happens?
32
Type 1 diabetes mellitus type of hypersensitivity? what happens?
33
Inflammatory bowel disease? type of hypersensitivity?
34
Role of (. ) in inflammatory bowel disease?
35
Principles of immunotherapy