L8 Viral Exanthems Flashcards

(49 cards)

1
Q

Etiology of Measles/Rubeola

A

Paramyxovirus

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2
Q

Symptoms of Measles/Rubeola

A

3Cs (cough, coryza-rhinitis, conjunctivitis), Koplik spots (enanthem in mouth), fever (105+), maculopapular Blanchable rash that spreads from head to toe and spares palms and soles

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3
Q

Koplik spots

A

Cluster of tiny bluish-white papules on buccal mucosa, “grains of salt on a red background”

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4
Q

Complications of Measles/Rubeola

A

Common is diarrhea or otitis media, more severe is pneumonia, encephalitis or subacute sclerosing panencephalitis

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5
Q

Subacute Sclerosing Panencephalitis

A

7-10 years after Measles, fatal degenerative disease of CNS, behavioral and intellectual deterioration, seizures

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6
Q

Treatment of Measles/Rubeola

A

Symptomatic treatment only, sometimes vitamin A or ribavirin

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7
Q

Etiology of erythema infectiosum(fifth disease)

A

Parvovirus B-19

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8
Q

Symptoms of erythema infectiosum

A

Facial rash (erythematous malar rash) called “slapped cheek” which is then followed by lacy, pink macular rash over body (trunk and extensor surfaces) 2-3 days later, starts with non-specfic flu-like sxs

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9
Q

Complications of erythema infectiosum

A

Rare but transient aplastic crisis, in pregnancy can be hydrops fetalis and/or fetal loss

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10
Q

Etiology of Rubella

A

Rubella virus

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11
Q

Transmission of Rubella

A

Inhaled large particle aerosols

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12
Q

Symptoms of Rubella

A

“3 day Measles” with a erythematous papules and purpura, head to toe progression, pinpoint/pink maculopapules, may have arthritis

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13
Q

Complications of Rubella

A

Encephalopathy, birth defects in pregnant women that lead to congenital rubella syndrome (blueberry muffin rash, hearing loss, mental retardation, CV and ocular defects)

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14
Q

Etiology of roseola infantum

A

Most commonly herpes virus 6 (HHV 6)

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15
Q

Symptoms of roseola infantum

A

High fever for 3-5 days and abruptly ends the an abrupt blanching pink/erythematous maculopapular rash (starts at neck and trunk and spreads to face then extremities)

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16
Q

Etiology of hand, foot and mouth disease

A

Coxsackie A16 virus

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17
Q

Transmission of hand foot mouth disease

A

Oral ingestion of virus (fecal oral or oral/respiratory secretions)

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18
Q

Symptoms of hand foot and mouth

A

Oral exanthem and enanthem on hand, feet and buttocks, vesicles may ulcerate

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19
Q

Etiology of molluscum contagiosum

A

Poxvirus

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20
Q

Symptoms of molluscum contagiosum

A

Flesh colored, pearly, papules with umbilication, located anywhere except palms and soles

21
Q

Etiology of condylomata acuminatum or verruca vulgaris (warts)

22
Q

Presentation of condylomata acuminatum

A

Classic cauliflower like lesions, perinatal growth, mild pruritis

23
Q

Etiology of varicella

A

Varicella-zoster virus, a herpes virus

24
Q

Symptoms of varicella

A

Generalized vesicular rash that is pruritic, with fever, malaise, pharyngitis or anorexia

25
3 main stages of varicella
Diagnose to see all 3 at same time, papules, ulcer and blister
26
Etiology of herpes zoster (shingles)
Varicella zoster virus
27
Transmission of Measles/ Rubeola
Infectious droplets spread by cough, sneeze or close breathing (stays for up to 2 hours)
28
Transmission of erythema infectiosum
Respiratory secretions
29
Transmission of molluscum contagiousum
Direct physical contact and contact with contaminated fomites, also autoinoculation
30
Treatment of molluscum contagiousum
Best option is no treatment, popophyllotoxin cream at home (not for pregnant women)
31
Treatment of condyloma acuminatium
Topical (podophyllin, immunotherapy or surgery
32
Tzanck smear
Use to show multinucleated giant cells associated with 3 stages of varicella
33
Timeline for return to school after varicella
Only contagious until all legions are crusted
34
Pattern of Shingles
Dormant HZV follows the dermatome of a specific sensory ganglion, unilateral
35
Symptoms of herpes zoster
Prodrome has acute, neuritic pain preceding eruption by 3-5 days, rash is ACTIVE and is development of grouped vesicles on an erythematous base
36
Complications of herpes zsoter
Post herpetic neuralgia, herpes zoster opthalmicus, acute retinal necrosis or nerve palsies
37
Post herpetic neuralgia
Lancinating, neuritic pain that can last months/yrs after resolution of lesions
38
Herpes zoster ophthalmicus
Sight-threatening linked to trigeminal ganglion activation, see hutchinson's sign
39
Hutchinson's sign
Trigeminal pattern of vesicles that go to the tip of the nose, HZV
40
Treatment of herpes zoster
Start within 72 hours, use antivirals (famciclovir or valacyclovir), might need to manage pain with narcotics
41
Infectious precautions of herpes zoster
Patient can transmit varicella to seronegative patients through contact with skin lesions
42
Types of HSV
HSV-1 (herpes labialis, cold sores), HSV-II (herpes genitalis, sexually), symptoms CAN flip between
43
Primary presentation of HSV-1
Gingivostomatitis, pharyngitis, severe mouth pain and fever
44
Pathogenesis of HSV
Virus can remain latent following primary infection and can be reactivated by change in immune status
45
Presentation of HSV
Prodrome of tingling, burning or pruritus, lesions appear as grouped vesicles on an erythematous bases (may see crusting)
46
Complications of HSV
Erythema multiforma, eczema herpaticum, recurrent aseptic meningitis
47
Treatment for chronic suppression of HSV
Antivirals with reassessment at 4-6 mos
48
Lipoma
Soft, mobile, non-tender subcutaneous soft-tissue tumor
49
Epidermal inclusion cyst
Soft, mobile, fluctuant nodule, sometimes central punctum and can be painful