L81 - Drugs affecting airway structure and function 1 Flashcards
(7 cards)
1
Q
Define Asthma
A
Chronic inflammatory disorder of the airways
chronic inflammation is associated with airway hyperresponsiveness that leads to recurrent episodes of wheezing , breathlessness, chest tightness, and coughing
2
Q
Host Factors of Asthma
A
Genetic - atopy - airway hyperresponsiveness Gender Obesity
3
Q
Environmental Factors of Asthma
A
Indoor Allergens Outdoor allergens Occupational sensitizers Tobacco smoke Air pollution Respiratory infections Diet
4
Q
What do Preventers prevent?
A
Bronchial wall oedema (swelling encroachment on lumen)
Mucus hypersecretion (occlusion of lumen)
5
Q
What to Relievers/controllers/preventers prevent?
A
Airway smooth muscle shortening (narowing of lumen)
6
Q
What does load decrease suring expiration cause?
A
increase in airways resistance
increase likelihoo
7
Q
Unloaded muscles shorten _______.
A
faster
