L9: Respiratory & Oxygenation Flashcards
(197 cards)
What are 3 steps in the process of oxygenation?
Ventilation, perfusion, and diffusion
The exchange of respiratory gases occurs between the ___________ and the ________.
environment and the blood
What is Respiration?
the exchange of oxygen and carbon
dioxide during cellular metabolism.
Where in the lungs does is oxygen from the atmosphere get exchanged for carbon dioxide?
alveoli -
specifically the alveolar capillary membrane
How do the diaphragm and intercostal muscles work together during inspiration?
The diaphragm and external intercostal muscles contract to create a negative pleural pressure and
increase the size of the thorax for inspiration.
Is Intrapleural pressure less than or greater than atmospheric pressure during inspiration?
Intrapleural pressure is negative, or less than atmospheric pressure, which is 760 mm Hg at sea level.
For air to flow into the lungs, intrapleural pressure becomes _______________.
more negative, setting up a pressure gradient between the atmosphere and the alveoli.
Ventilation
The process of moving gases into
and out of the lungs
Perfusion
The ability of the cardiovascular system to pump oxygenated blood to the tissues and return deoxygenated blood to the lungs
Diffusion
Exchange of respiratory gases in
the alveoli and capillaries
The major inspiratory muscle of respiration is
the diaphragm
The diaphragm is innervated by the _________.
phrenic nerve, which exits the spinal cord at the fourth cervical vertebra.
Diffusion moves respiratory gases from one area to another by ___________.
concentration gradients
Work of breathing is?
The effort required to expand and contract the lungs.
Inspiration
active process stimulated by chemical receptors in the aorta.
Expiration
a passive process that depends on the elastic recoil properties of the lungs
Surfactant
chemical produced in the lungs to maintain the surface tension of the alveoli and keep them from collapsing
Atelectasis
collapse of the alveoli that prevents normal exchange of oxygen
Compliance
ability of the lungs to distend or expand in response to increased intraalveolar pressure
Airway resistance
the increase in pressure that occurs as the diameter of the airways decreases from mouth/nose to alveoli. Any further decrease in airway diameter by bronchoconstriction can increase airway resistance
What can cause an increase in airway resistance?
Diseases causing airway obstruction such as ASTHMA and tracheal edema.
The amount of energy expended on breathing depends on ___________.
rate and depth of breathing, the ease with which the lungs can be expanded (compliance), and airway resistance.
What happens in patients with advanced chronic obstructive pulmonary disease (COPD)?
They lose the elastic recoil of the lungs and thorax. As a result, the patient’s work of breathing increases.
Pulmonary diseases that decreased surfactant production can sometimes cause _________?
atelectasis