[Lab] Human Chromosome Flashcards
(33 cards)
Group A chromosome numbers + centromere position
1-3, metacentric / submetacentric
Group B chromosome numbers + centromere position
4-7, very submetacentric / submetacentric
Group C chromosome numbers + centromere position
8-12 + X, slightly to very submetacentric
Group D chromosome numbers + centromere position
13-15, acrocentric
Group E chromosome numbers + centromere position
16-18, mostly submetacentric
Group F chromosome numbers + centromere position
19-20, metacentric
Group G chromosome numbers + centromere position
21-22 + Y, acrocentric (Y = very submetacentric)
chromosome associated with Rh blood group
chromosome 1
chromosome associated with spontaneous abortion
chromosome 2
chromosome associated with phenylketonuria
chromosome 4
chromosome associated with Cri du Chat syndrome
chromosome 5
chromosome associated with MHC locus
chromosome 6
chromosome associated with histone and collagen synthesis
chromosome 7
chromosome associated with Warkany syndrome
chromosome 8
chromosome associated with globulin production
chromosome 11
chromosome associated with Patau syndrome
chromosome 13
chromosome associated with Prader-Willi syndrome
chromosome 15
chromosome associated with Edward syndrome
chromosome 18
chromosome associated with Down syndrome
chromosome 21
type of clinical cytogenetics used in diagnosis of heritable genetic abnormalities
routine / constitutional testing
type of clinical cytogenetics used in detection of acquired or somatic abnormalities
cancer diagnosis
3 steps for preparation of human metaphase chromosome
- culture initiation
- culture maintenance
- cell harvest
4 possible sources of specimen collection and handling
- peripheral blood
- bone marrow aspirates
- amniotic fluid
- solid tissue biopsies
what is sodium heparin used for?
prevention of clotting of specimens
