Laboratory Findings with Diseases Flashcards
(20 cards)
A result of genetic abnormalities or lifestyle imbalances in known as what?
Dyslipidemias
How are Dyslipidemias NOT defined?
Not defined by Specific Genetic Defect associated with the abnormality
What are the positive risk factors the NCEP devoleped?
> = 45 for men, >= 55 for women OR Premature Menopause
Family history of Premature CHD
Cigarettes
Hypertension
What are the concentrations associated with positive risk?
LDL-C: >= 160 with <= 1 factor
LDL-C: >=130 with >= 2 factors
LDL-C: >= 100 with CHD or equivalent
HDL-C: < 40
Atherogenic Dyslipidemia, Elevated blood pressure, elevated plasma glucose, and diabetes mellitus are all what?
Risk factors equivalent to Coronary Heart Diesease
What are the negative risk factor concentrations?
HDL-C: >= 60
LDL-C < 100
List the reference ranges for normal Lipoprotein measurements
Total Cholesterol: 140 - 200 mg/dL
HDL-C: 40 - 75 mg/dL
LDL-C: 50 - 130 mg/dL
Triglycerides: 60 - 150 mg/dL
A plasma lipid is elevated. What is responsible for this and what is this condition called?
Total Cholesterol & Triglycerides
Hyperlipidemia
What did NCEP ATP III state in regards to Hyperlipidemia for Triglycerides?
< 150: Borderline High
150 - 200: High
200 - 500: Very high (Acute Pancreatitis)
What is in a symptomless state that is associated with the development of Atherosclerosis?
Hyperlipidemia
Viewed as an inflammatory disease, what is almost always the result of Atherosclerosis?
Coronary Artery Disease
What plays a central role in promoting plaque formation?
Low Density Lipoprotein
An elevation of serum Lipoprotein concentrations
Hyperlipoproteinemia
What is the abnormality closely linked to heart disease?
Hypercholesterolemia
Hypercholesterolemia is caused by what?
A lack or defect in active LDL receptors
A result of genetic or hormonal abnormalities
Hypertriglyceridemia
Why is Hypertriglyceridemia potentially life threatening?
It can cause Acute or Recurrent Panreatitis
What is defined as the presence of elevated levels of Total Cholesterol and Triglycerides?
Combined Hyperlipoprotenemia
How do we establish a risk for CHD?
A medical history of High Lipid and Lipoprotein test results
Who is recommended for Cholesterol Screening?
Those over 20 years of age
Recommended every 5 years
