**Acid phosphatase (pap)
inc: prostatic carcinoma
**A/G ratio
Reversed: MM
**Alk phosphatase
Inc: osteoblastic lesions, hepatic dz, HPT
Bone/liver
Amylase
Inc: acute pancreatitis
F/ANA
Collagen dz (SLE, scleroderma)
Antistreptolysin O (ASO) titre
Inc: rheum fever, acute glomerulonephritis
Pos strep
Bilirubin increase
Direct: hepatitis, duct obstruction
Indirect: hemolytic dz
BUN (blood urea nitrogen) inc
renal dz, dehydration, hypotension, uto
Ca increase
muscle weakness, hyperparathyroidism, hypovit d, mets
CPK (creatine phosphokinase)
CK BB: brain tissue
CK MB: myocardial tissue
CK MM: skeletal muscle (md)
inc: musc necrosis
CRP increase
kidney dz, hypovolemic shock
ELISA
SCREENING for AIDS
ESR increase
infx, RA, TB, TA, MM
FTA (fluorescent treponema antibody)
present with syph
blood glucose increase
DM, cushings, renal/liver dz
CSF glucose
dec: meningitis, acute pyogenic infx
gamma-glutamyl transferase (GGT)
liver cell dysfx and alc induced liver dz
glucose tolerance test (GTT)
diabetes testing
**glycosylated hemoglobin
tests ability to use gluc over 2-3m period (monitor)
**paul bunnel (heterophile)
inc: mono, viral meningitis
*HCG increased
hydatidiform mole, choriocarcinoma, seminoma, mult pregnancy, testic teratoma
**HLA B27
marker on the 6th chromosome from birth
AS, reiters, PA, enteropathic arthritis (PEAR)
HDL cholesterol increase
ow risk of coronary heart dz
I-131 uptake increase
iodine
hyperthyroidism, endemic goiter
**immunoelectrophoresis
m spike = MM
ketones
diabetic acidosis, starvation
LDH (lactase dehydrogenase) increase
MI, CHF, musc dystrophy
**lipase
inc: acute pancreatitis
lipids (cholesterol)
inc: early starvation, DM
dec: late starvation, liver dz
lipids (triglycerides)
inc: hyperlipidemia, DM, atherosclerosis
dec: cirrhosis, malabsorption
LE cell
active SLE
phosphorus increase
acromegaly, kidney dz, hypervit D
protein increase
MM, diabetic acidosis
protein (CSF)
inc: viral meningitis
prothrombin times
inc: vit K def, hepatocellular dz
RA latex
+: RA, SLE, TB, CA, sjogren, still’s
SGOT/AST
serum glutamic oxaloacetic transaminase
inc: MI, liver cond, MD
SGPT/ALT
serum glutamic pyruvic transaminase
inc: hepatitis, MI
T3: triodothyronine
T4: thyroxine
inc: hyperthyroidism, pregnancy
dec: hypothyroid, cirrhosis
TPI (treponema pallidum immobilizing agent)
syph
uric acid
inc: gout, renal failure
VDRL (venereal dz research lab
serologic screening for syph
** western blot
SPECIFIC test for AIDS
Ca decrease
muscle tetany, chvostck sign (opp above), renal failure, malnutrition
CRP decrease
musc dystrophies
BUN decrease
hepatic dz, pregnancy
Liver and kidneys
ESR decrease
sickle cell anemia, polycythemia
blood glucose decrease
insulin overdose, addison, starvation
HCG decrease
ectopic pregnancy, threatened abortion
HDL cholest decrease
high risk of coronary heart dz
I-131 uptake decrease
iodine
hypothyroidism, thyroid ca
LDH decrease
cancer therapy
phosphorus decrease
rickets, hypovitaminosis D, hyperparathyroidism
protein decrease
liver dz, kidney syndromes