LE 1 Flashcards
(151 cards)
- Which of the following statements is characteristic of the ovary?
A) The granulosa layer of cells of a secondary follicle is highly vascularized
B) The theca externa has LH receptors and produces androstenedione
C) The theca interna secretes androstenedione in response to LH
D) The basal lamina separates the primary oocyte from the granulosa
E) The secondary follicle contains a secondary oocyte
C) The theca interna secretes androstenedione in response to LH
Rationale: The theca interna layer of the ovarian follicles contains LH receptors. Upon stimulation by LH, the theca interna cells produce androgens, primarily androstenedione, which is then used by granulosa cells to synthesize estrogen. The other options either inaccurately describe ovarian structures or their functions.
- Is a muscular layer that is regulated by ovarian hormones and oxytocin which causes increased force and rate of uterine contractions?
A) Endometrium
B) Myometrium
C) Perimetrium
B) Myometrium
Rationale: The myometrium is the muscular layer of the uterus influenced by ovarian hormones (estrogens and progesterone) and oxytocin. These influences cause changes in the contractility of the myometrium, particularly important during labor.
- Patient EF is a G1PO 14 weeks age of gestation. When is the earliest time she can expect quickening?
A) 16 weeks
B) 14 weeks
C) 20 weeks
D) 18 weeks
D) 18 weeks
- A 28-year-old primigravid, on her 24th week AOG computed from her last menstrual period, came to your clinic for her first prenatal checkup. Her fundic height (uterine measurement from symphysis pubis to funds) was noted to be 30 cm. What is the next best step in the management of this patient?
A) Reassure patient that it is a normal finding, and she could come back after 1 month for her regular check-up
B) Request for an ultrasound to determine or confirm age of gestation, or detect any abnormality
C) Advise patient to start taking protein supplements in order for the baby to catch up in size
D) Inform the patient that her correct age of gestation is 30 weeks, and not 24 weeks
B) Request for an ultrasound to determine or confirm age of gestation, or detect any abnormality
Rationale: A fundal height of 30 cm at 24 weeks suggests a measurement that is larger than expected, possibly indicating incorrect dating, a large fetus, multiple gestation, or other abnormalities. An ultrasound would provide more precise information about gestational age and assess for complications.
- Milk protein is produced by which of the following mechanisms?
A) Paracrine secretion
B) Merocrine secretion
C) Autocrine secretion
D) Apocrine secretion
D) Apocrine secretion
Rationale: Milk protein secretion in mammary glands occurs by apocrine secretion, where part of the cell cytoplasm is released with the secretory product. This is typical in the mammary gland epithelial cells.
- Each breast consists of
A) 1 mammary gland
B) 2 mammary glands
C) 5 mammary glands
D) 20 mammary glands
D) 20 mammary glands
- What is the fetal lie?
A) Cephalic
B) Breech
C) Transverse
D) Shoulder
E) Longitudinal
F) Oblique
G) Compound
C) Transverse
- Elevation of body temperature among pregnant women is secondary to:
A) Thermogenic effect of progesterone
B) Thermogenic effect of estrogen
C) Thermogenic effect of testosterone
D) Thermogenic effect of human chorionic gonadotropin
A) Thermogenic effect of progesterone
Rationale: The elevation in body temperature during pregnancy can be attributed to the thermogenic effects of progesterone, which is elevated throughout pregnancy and increases the basal metabolic rate.
- A 22-year-old female experienced her first menstrual cycle at age 14. Until recently, she had a normal regular menstrual cycle with an interval of 30 days. Six months ago, she began training for a marathon. She runs roughly 115 miles per week and as a result of her training regimen, she has lost 20 pounds. She has not menstruated for the past 3 months. Given these findings, what is the most likely endocrine explanation for her amenorrhea?
A) Absence of GRH surge
B) Prolonged elevation of follicle-stimulating hormone
C) Increase in plasma leptin
D) Absence of a surge in luteinizing hormone
E) Abnormally elevated plasma estradiol
D) Absence of a surge in luteinizing hormone
Rationale: Intense physical activity and significant weight loss can lead to hypothalamic dysfunction, which often manifests as a disruption in the normal pulsatile secretion of GnRH (gonadotropin-releasing hormone) from the hypothalamus. This disrupts the normal surge of LH necessary for ovulation, leading to amenorrhea.
- Which of the following hormones is involved in the development of the mammary glands and ducts, thus preparing the body for pregnancy?
A) Prolactin
B) Oxytocin
C) Progesterone
D) Inhibin
C) Progesterone
Rationale: Progesterone, along with estrogen, plays a crucial role in the development of the mammary glands and ducts during pregnancy. Progesterone supports glandular differentiation and growth, preparing the breasts for lactation post-delivery.
- True about the layers/coat of the wall of the uterine body:
A) The outer layer consists of peritoneum supported by a thick layer of connective tissue
B) The inner mucosal coat becomes greatly distended during pregnancy
C) The functionalis layer of the endometrium regenerates the basalis layer following each menses
D) The amount of muscle fiber in the middle coat is greater in the inner than in the outer wall
D. The amount of muscle fiber in the middle coat is greater in the inner than in the outer wall
Explanation: The middle coat of the uterine body, known as the myometrium, consists predominantly of smooth muscle bundles. These bundles are more concentrated in the inner layer than in the outer layer of the uterine body. This structural arrangement facilitates the effective contraction of the uterus during childbirth and menstruation. The statement correctly reflects the anatomical distribution of muscle fibers in the uterus, aligning with the information about the increased muscularity of the inner wall compared to the outer wall.
- Where do the uterus and the fallopian tubes arise from?
A) Wolffian ducts
B) Wartonian ducts
C) Mesonephric ducts
D) Mullerian ducts
D) Mullerian ducts
Rationale: The uterus and fallopian tubes, along with the upper part of the vagina, develop from the Müllerian ducts (paramesonephric ducts). This is the fundamental embryologic origin of most of the female reproductive tract.
- Which of the following is characteristic of the stratum basale?
A) Contains cells that are highly responsive to progesterone
B) Includes the uterine surface epithelium
C) Contains coiled arteries
D) Is the layer that undergoes shedding
E) Contains cells that replace the surface epithelium after menstruation
E) Contains cells that replace the surface epithelium after menstruation
Explanation: The stratum basale, or basal layer, of the endometrium is the layer that remains following menstruation and is responsible for regenerating the functional layer (stratum functionalis) that is shed during menstruation. This layer contains the necessary cells and structures to rebuild the surface epithelium and glandular components of the endometrium each cycle, preparing it again for potential implantation.
- A 22-year-old G1P0 at 16 weeks AOG, has ruptured tubal pregnancy and presents with hypovolemia secondary to hemorrhage. The implantation of the conceptus most likely is in the:
A) Infundibulum
B) Ampulla
C) Isthmus
D) Interstitium
B) Ampulla
Rationale: The most common site for an ectopic pregnancy is the fallopian tube, particularly the ampulla section. This area provides a common site for implantation outside the uterus due to its relative length and mobility.
- The stroma of the ovary consists of blood vessels, nerves, muscle fibers, and a type of protein called:
A) Fibrin
B) Collagen
C) Albumin
B) Collagen
Rationale: The stroma of the ovary is composed primarily of connective tissue, which includes a high concentration of collagen. Collagen provides structural integrity and support to the ovarian tissues.
- A patient at her 23rd week age of gestation came to your clinic for the first time for her prenatal check-up. Upon doing obstetric examination, you noted that the fundic height is 27 cm. Which of the following is a possible diagnosis?
A) Intrauterine growth restriction
B) Oligohydramnios
C) Polyhydramnios
D) Normal findings in pregnancy
C) Polyhydramnios
D) Normal findings in pregnancy
Rationale: Fundal height measurements in pregnancy are roughly equivalent to the week of gestation plus or minus 2 cm. At 23 weeks, a fundal height of 27 cm is within normal limits.
- After an egg is ovulated, the remaining mass is called a:
A) Theca folliculi
B) Corpus luteum
C) Vesicular folliculi
D) Corpus albicans
B) Corpus luteum
Rationale: After ovulation, the follicle transforms into the corpus luteum. This structure is crucial for producing progesterone, which supports the early stages of pregnancy until the placenta can take over.
- In the sexually mature female, ovulation is preceded by a dramatic change in luteinizing hormone. What would be the factor and the change in its release that is obligatorily linked in the change in LH before ovulation?
A) Increase in dopamine
B) Decrease in gonadotropin-releasing hormone
C) Decrease in dopamine
D) Increase in gonadotropin-releasing hormone
E) Increase in inhibin
D) Increase in gonadotropin-releasing hormone
Rationale: Ovulation is closely linked to a surge in gonadotropin-releasing hormone (GnRH), which in turn stimulates a sharp increase in luteinizing hormone (LH). This LH surge triggers ovulation.
- Which of the following is characteristic of the secretory phase of the menstrual cycle?
A) It produces ischemia and necrosis of the stratum functionalis
B) It is controlled by estrogen
C) It ends upon the arrival of ovulation
D) Endocervix is sloughed off during this phase
E) Uterine gland lumens are filled with secretions
E) Uterine gland lumens are filled with secretions
Rationale: During the secretory phase of the menstrual cycle, following ovulation and under the influence of progesterone, the uterine glands become more tortuous and their lumens fill with secretions that are important for nourishing an implanted embryo.
- The cervix is composed mainly of which of the following components?
A) Smooth muscle
B) Elastin
C) Proteoglycan
D) Collagen
D) Collagen
Rationale: The cervix is primarily composed of dense connective tissue, which includes a high content of collagen. Collagen provides structural strength and supports the cervix, especially important during pregnancy and childbirth.
- A 20-year-old primigravid, 4-5 weeks age of gestation, came to your clinic anxious because her ultrasound showed only a gestational sac, with still no fetal heart beat noted. How would you advise this patient?
A) She has evidence of an anembryonic pregnancy and needs a dilation and curettage done as soon as possible to remove the products of conception.
B) You tell the patient that she is not pregnant.
C) Reassure the patient that fetal heart beat will manifest at around 6 weeks age of gestation, and that she may opt to repeat her transvaginal ultrasound after about 2-3 weeks.
D) The ultrasound showed evidence of intrauterine fetal demise.
C) Reassure the patient that fetal heart beat will manifest at around 6 weeks age of gestation, and that she may opt to repeat her transvaginal ultrasound after about 2-3 weeks.
Rationale: At 4-5 weeks of gestation, it’s common not to detect a fetal heartbeat. It is typically visible by around 6 weeks of gestation. Reassuring the patient and suggesting a follow-up ultrasound in 1-2 weeks is appropriate to confirm normal development.
- When the myoepithelial cells contract, milk is forced from the alveoli to the nipple. Which of the following hormones causes the myoepithelial cells to contract?
A) Estrogen
B) Oxytocin
C) Progesterone
D) Inhibin
B) Oxytocin
Rationale: Oxytocin is the hormone responsible for causing the contraction of myoepithelial cells around the milk alveoli, which helps to express milk from the alveoli through the milk ducts to the nipple.
- Pap smear should be done on all asymptomatic pregnant patients during her first prenatal checkup.
A) False
B) True
A) False
Rationale: Pap smear screening is generally not recommended during the first prenatal visit unless it is due based on routine screening intervals or if there are specific indications. Pregnancy does not increase the risk of cervical cancer, and routine screening can be safely deferred until postpartum if recent results are normal.
- What is the fetal presentation?
A) Cephalic
B) Breech
C) Transverse
D) Shoulder
E) Longitudinal
F) Oblique
G) Compound
D) Shoulder