LE 1 Flashcards

(60 cards)

1
Q

Due to a hypoxic event caused by hemorrhage DURING pregnancy…

A

Sheehan’s syndrome.

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2
Q

Single contour of breast and areola.

Adult hair in thickness and texture; midline distribution.

A

B5

PH4

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3
Q

TRUE OR FALSE:

Blind girls have menarche earlier.

A

TRUE

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4
Q

TRUE OR FALSE:

Peak heigh velocity is earlier in girls than in boys.

A

TRUE

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5
Q

Increase in gonadal estrogen.

A

Gonadarche

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6
Q

Irregular, prolonged, excessive menses

A

Menometrorrhagia

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7
Q

Regular, prolonged, excessive menses

A

Menorrhagia

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8
Q

How many days of no menses to consider amenorrhea?

A

90 days

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9
Q

17 years old never had menses. Breasts and pubic hair are B1PH1. Initial diagnosis?

A

Primary Amenorrhea

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10
Q

XX Karyotype

A

Mullerian agenesis/anomalies

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11
Q

XY Karyotype

A

Androgen insensitivity (Testicular feminization)

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12
Q

Formation of intrauterine adhesions secondary to uterine manipulation.

A

Ashermann’s Syndrome

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13
Q

Most common cause of primary amenorrhea

A

Gonadal dysgenesis
Turner’s syndrome
45X

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14
Q

Uterus present
Breast development absent
Elevated progesterone levels

A

17 a hydroxylase deficiency

46XX

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15
Q

Most common non-prolactin secreting tumor of the pituitary

A

Chromophobe adenoma

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16
Q

Compartment IV is disoders of ____________?

A

Hypothalamus

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17
Q

Use of OCPs inhibit ovulaion by acting both at these two sites.

A

Hypothalamus & Pituitary

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18
Q

Increase in dopamine will ___________ LH/FSH levels

A

Decrease (due to inhibition of GnRH release)

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19
Q

Diagnostic marker for patients with anorexia nervosa

A

Serum T3 levels

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20
Q

Most common female endocrine disorder

A

PCOS

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21
Q

Rotterdam Criteria

A
  1. Oligo-ovulation/Anovulation
  2. Ultrasound findings of polycystic ovaries
  3. Hyperandrogenism
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22
Q

Hypothalamic pituitary dysfunction has Estradiol levels of

A

> 40 pg/nl

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23
Q

Normal menstruation:
Interval
Amount
Duration

A

21-35 days
35 ml
4-7 days

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24
Q

An oocyte arrested at prophase

Enveloped by a single layer of spindle-shaped pregranulosa cells, surrounde by a basement membrane

A

Primordial follicle

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25
The variable phase of menstruation.
Follicular
26
Completed by day 5 of the follicular cycle
Secretion of dominant follicle
27
It causes detachment of oocyte to the cumulus from the granulosa cells
Plasmin
28
How many hours does an oocyte wait for fertilization?
48-72 hrs
29
Dominant steroid in the luteal phase
Progesterone
30
Hypothalamic GnRH neurons are concentrated mostly in the:
Arcuate nucleus
31
Two things that control the menstrual cycle:
1. Frequency of pulses | 2. Amplitude of pulses
32
Difference of gonadotropins with TSH
Beta subunit
33
Act on theca cells to induce steroidogenesis
LH
34
FSH acts on these cells
Granulosa
35
Stimulates thecal androgen production
Inhibin
36
Causes enlargement of labia majora and minora, uterus, increased fundal to cervical ratio Cornification of vagina Growth of ductal system of breasts
Estrogen
37
Decreases tubal mobility Thickening of cervical mucus Stabilizes endometrium
Progesterone
38
Layer of the endometrium that desquamates at the time of menses
Stratum functionale
39
1st endocrinologic sign of menopause
Decreased levels of inhibin
40
Menstrual cycle is controlled by the...
HPO axis
41
Interval between menstruation and ovulation.
12-16 days
42
Desquamation of the endometrium mainly occurs in the....
Uterine fundus
43
Occurs because of estrogen-progesterone withdrawal
Menstrual bleeding
44
2 mechanisms for hemostasis after menstruation
Hemostatic plug formation | Vasoconstriction
45
Reported to occur in 10% of ovulatory women
Ovulatory DUB
46
Reduced levls of PGF2 alpha | Normal levels of PGE
Anovolutary DUB
47
Predominant cause of DUB among postmenarcheal and perimenopausal years
Anovulatory DUB
48
FIGO classification | Anatomic causes
PALM
49
L in PALM
Leiomyoma
50
N in COIEN
Not yet classified
51
C in COEIN
Coagulopathy
52
What is PALM and COEIN
Polyp Adenomyosis Leiomyoma Malignancy ``` Coagulopathy Ovulatory dysfunction Endometrial Iatrogenic Not yet classified ```
53
Most objective diagnostic modality
Transvaginal Ultrasound
54
To confirm presence of submucous myomas and polyps
Saline infusion sonography
55
Evaluate endometrial cavity
Hysteroscopy
56
Blind procedure performed under anesthesia
D&C
57
Management for AUB
Stop bleeding
58
Not for acute control of bleeding
GnRH agonists
59
Androgenic steriod, rarely used
Danazol
60
MOA is photovaporization with Nd-YAG laser
Endometrial ablation