Learning and Memory Flashcards

1
Q

instrumental activities of daily living

A

not necessary for fundamental functioning, but let an individual live independently in a community

ex: managing money, meal prep, etc.

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2
Q

activities of daily living

A

routine activities that people tend to do everyday without assistance

eating, bathing, dressing, walking, toileting

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3
Q

essential brain structure for memory

A

hippocampus

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4
Q

H.M.

A

fine working memory, poor explicit memory

bilateral medial temporal lobes removed at age 20 due to intractable seizures

anterograde amnesia (inability to learn new information and hold onto it after surgery)

retrograde amnesia (inability to remember events prior to surgery (10 yrs)

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5
Q

memory

A

effect of past experiences on present perceptions and behavior

some are effort-full and some are effortless

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6
Q

content feature of memory

A

episodic, semantic, explicit, implicit

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7
Q

memory for personal experiences

A

episodic memory

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8
Q

memory for general information not specifically tied to a personal experience

A

semantic memory

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9
Q

declarative; something you have a conscious recollection of; represented in recollection

A

explicit memory

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10
Q

non-declarative; procedural; unconscious recollection of past events; represented in behavior/priming, classical conditioning

A

implicit memory

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11
Q

storage capacity/duration feature of memoery

A

perceptual, short-term/working, long-term

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12
Q

“iconic” or “sensory”

very fleeting, lasts milliseconds; neuropsychologists not interested

A

perceptual memory

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13
Q

thought to have a finite amount of storage (7 +/- 2 bits); degrades over a period of seconds unless rehearsed to transferred to long-term memory

A

short-term memory (working memory)

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14
Q

unlimited capacity and relatively permenant

A

long-term memory

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15
Q

stages feature of memory

A

registration/encoding
storage/consolidation/maintenance
retrieval/recognition

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16
Q

learning new information (how well do you hold onto something new and how well do you learn with repetition)

A

registration/encoding of memory

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17
Q

organize information in a meaningful way to store so that it can be used later

A

storage/consolidation/maintenance of memory

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18
Q

how we access the information that we hold onto

A

retrieval/recognition of memory

19
Q

implicit memory effect where exposure to one stimulus influences response to another stimulus

A

priming

20
Q

semantic priming

A

observation that a response to a target is faster when it is preceded by a semantically related prime compared to an unrelated prime

21
Q

perceptual priming

A

based on the form of stimulus and enhanced by the match between early and later stimuli

22
Q

explicit memory is mediated by which two systemes

A

temporal and diencephalic

impaired in amnesia

23
Q

implicit memory depends on what structures

A

structures outside of the temporal lobes of brain

preserved in amnesia

24
Q

H.M. evidence for implicit memory preservation in amnesia

A

showed an ability for improved performance on a maze learning task despite being able to remember the task or the trainer

25
Q

medial temporal lobes create a highly interconnected circuit with structures in ________ _______ and the _______

A

limbic system (mamillary bodies, dorsal medial nucleus of thalamus) and neocortex

26
Q

primary inputs to hippocampus are _______ ____

A

entorhinal cortex

27
Q

preserved memory systems when medial temporal damage occurs

A

implicit memory, perceptual memory, short-term memory, registration/encoding

28
Q

impaired memory systems when medial temporal damage occurs

A

explicit (episodic and semantic), long-term memory, storage/consolidation/maintenance, retrieval/recognition

29
Q

verbal episodic memory tasks or explicit memory tasks are associated with…

A

left medial temporal activation

30
Q

non-verbal episodic memory tasks are associated with…

A

bilateral medial temporal activation

31
Q

problem with retrograde amnesia

A

simple medial storage model cannot explain

some explicit memory is preserved in amnesia (early memories) and earlier-acquired memories better preserved than later-acquired memories (GRADED RETROGRADE AMNESIA)

32
Q

implications of graded retrograde amnesia

A

medial structures not necessary for storage/maintenance once consolidation has occurred

consolidation occurs over a long period

33
Q

implications of anterograde amnesia

A

medial structures are necessary for consolidation of new experiences

34
Q

according to “time-dependent explivit memory deficits in amnesia,” medial temporal structures are important for

A

retention of memory for some period of time but most important for storage of memory elsewhere

35
Q

Multiple Trace Theory of Explicit Memory

A

behaviorally-relevant input firing patterns from sensory cortex are “tagged” by rhinal-hippocampal activity as a “trace”

recurrence of one element of the trace triggers activation of others via the shared “tag” which reactivates and reinforces the earlier, complete pattern

over time, reactivation becomes independent of rhinal-hippocampal activity and can occur with only neocortically-based, sensory activation

36
Q

experiment done on 50 normal controls: asked to recall news events from 7 different time periods

tested activation for recent and remote events

A

recollection of REMOTE facts results in more NEOCORTICAL activation

recollection of RECENT facts results in more HIPPOCAMPAL activation

37
Q

a semantic memory impairment requires ________ damage

A

neocortical

38
Q

compared patients with lesions restricted to hippocampus vs. those with lesions that involved varying degree of the anterolateral temporal cortex (medial temporal lobe + patients)

given semantic memory tasks (told name and description and asked to point to matching object)

A

patients with HIPPOCAMPAL damage performed similar to controls on battery of tests

MTL+ patients (hippocampal and lateral temporal cortex damage) had more significant semantic memory deficits

39
Q

priming paradigm of healthy controls versus patients with mild Alzheimer’s

A

shown pictures of indoor and outdoors scenes
two conditions (novel and repeat)
require to press button if scene was outdoors
baseline: only see word PUSH
novel: see something they have never seen before
repeat: scene they’ve already seen

40
Q

novel versus repeat conditions

A

medial temporal regions and fusiform areas activated in correlation to better recognition memory

activation in parietal/occipital/cingulate areas associated with increased priming effect

41
Q

clinical assessment of episodic auditory verbal

A

prose recall (immediate and delayed)
word list learning (CVLT, HVLT, RAVLT)
verbal paired associates (“gold-walk,” “tire-feather”)

42
Q

clinical assessment of semantic memory

A

boston naming test

semantic fluency

43
Q

clinical assessment of episodic visuo-spatial

A

rey figure (immediate and delayed)
figure learning (BVMT-R)
WMS-III facial memory
WMS-III family pictures