learning from mistakes

Question 1

Interaction with Allopurinol

can allopurinol be used in renal imapirment?

Answer 1

azathioprine(increased effect of azathioprine)

Yes!

Question 2

AID- risk of pneumonia- what med is used for prophylaxis

Answer 2

Co-trimoxazole

Atovaquone is C/I

Question 3

fludrocortisone electrolyte disctubance

what to avoid with

Answer 3

hypokalaemia

methadone- risk of QT/Torsades de pointes

Question 4

colestyramine timins with food

Answer 4

1 hour before 4 hour after

Question 5

GTN tabs - how long do they provide symptomatic relief?

Answer 5

30 min

NO COTTON WOOL

DISCARD AFTER 8 WEEKS

Question 6

H pylori Tx

Answer 6

clarithromycin
Amoxicillin
PPI

if Pen allergic- metronidazole.

Question 7

Loperamide- max tabs/day

Answer 7

8 Tabs/day (16mg)

Question 8

Colchicine max G/ course

Time between courses

Answer 8

6g

3 days between acute courses

Question 9

perindopril dose timing

Answer 9

30-60 min before food

Question 10

bendroflumethiazide SE

Answer 10

• hypokalaemia
• hyperglycaemia
• hypercalcaemia
• herperuricaemia
• hyponatraemia

Question 11

high intensity statin

Answer 11

Atorva 20 -YES

Simva 40- NO

Question 12

metronidazole gel + warfarin

Answer 12

Increased INR

Question 13

Aminophylline- effect on potassium

Answer 13

HYPOKALAEMIA

Question 14

Prostaglandin analogues- counselling

Answer 14

Brown pigmentation

Question 15

Filgrastim- indication

Answer 15

NEUTROPENIA

Commonly used in chemo as it increases production of neutrophils

Question 16

pregnancy- which vit is advised to take at a dose of 10mcg/day

Answer 16

D

Question 17

why do we need vit D

Answer 17

To absorb calcium

in renal impairment- use activated form (calcitrol)

Question 18

levothyroxine dose timing

Answer 18

morning, 30 min before breaky/ caffeine.

Question 19

what is Oligouria

Answer 19

low vol urine

symptom of AKI

Question 20

Linezolid- monitoring

Answer 20

OPTIC NEUROPATHY(visual disturbance)

FBC

Question 21

Risk of long term trimethoprim

Answer 21

blood disorders

watch out for mouth ulcers etc

Question 22

isotretinoins- avoid which vitamin

Answer 22

VIT A

Question 23

first line tx for chronic stable plaque psoriasis

Answer 23

coal tar

Question 24

why are ACE- I cautioned in diabetes

Answer 24

lower glucose

Question 25

lethal comp of anaesthesia

Answer 25

malignant hyperthermia

Question 26

chemo- highly emetogenic

Answer 26

cisplatin | cyclophosphamide

Question 27

least emetogenic

Answer 27

vincristine

Question 28

vincristine SE

Answer 28

hair loss

Question 29

clindamycin- diarrhoea

Answer 29

stop | antibiotic associated colitis

Question 30

macrolides- nausea

Answer 30

normal

Question 31

MHRA Quinine

Answer 31

QT

Question 32

isotretinoin- giving blood

Answer 32

avoid | and for 1 month after

Question 33

threadworms- effect on children

Answer 33

Bed wetting waking at night

Question 34

antipsychotic weight gain

Answer 34

olanzapine clozapine quetiapine

Question 35

dithranol (for psoriasis)

Answer 35

staining

Question 36

CD -patient returns

Answer 36

denature prior to disposal authorised witness not required.

Question 37

purpuric skin rash- which AED

Answer 37

phenytoin

Question 38

HF- Diuretic

Answer 38

NOT K sparing furosemide best

Question 39

growth hormones schedual

Answer 39

CD 4 part 2

Question 40

baclofen ( should they be taken with ACE/B-Blocker?)

Answer 40

NO | Increases hypotensive effect

Question 41

Ganciclovir. when C/I

Answer 41

Low neut count

Question 42

bromocriptine (suppression of lactation)- risk when started

Answer 42

hypotensive reaction

Question 43

febuxostat

Answer 43

tx of gout prophylaxis and acute episodes SJS

Question 44

what schedual is midazolam

Answer 44

3

Question 45

methotrexate and trimethoprim

Answer 45

avoid

Question 46

what is in malarone? when to take

Answer 46

proguanil/atovaquone 1-2 days before during 1 week after

Question 47

lithium- how oftern to monitor LFTs

Answer 47

every 6 months

Question 48

sodium valproate

Answer 48

hepatotoxicity | pancreatitis.

Question 49

which drugs carry as risk of gingival hyperplasia?

Answer 49

ciclosporin phenytoin nifedipine

Question 50

which drugs increase saliva production

Answer 50

clozapine | neostigmine (anticholinesterase)

Question 51

which affect can phenobarb have on an infants

Answer 51

inhibits sucking reflex

Question 52

lorazepam schedual

Answer 52

cd4 | Lorazepam

Question 53

antimilarial to avoid in renal impairment

Answer 53

proguanil

Question 54

reversal agent for heparin toxicity

Answer 54

protamine sulphate

Question 55

which anti-diabetic should NOT be stopped during surgery

Answer 55

SGLT2- risk of DKA

Question 56

is a date legal req for a CD requisition

Answer 56

no

Question 57

sumatriptan and ssris- whats the risk

Answer 57

serotonin syndrome