Lec 12: Cerebellum

Question 1

Functional Division:

Vestibulocerebellum:

Receives input from where?

Answer 1

Vestibular apparatus and vestibular nuclei

Question 2

Vestibulocerebellum send output to where?

Answer 2

vestibular nuclei

Question 3

Vestibulocerebellum output reaches motor neurons via…

Answer 3

The vestibulospinal tracts and tracts that coordinate eye and head movements (spinal thalamic tract)

Question 4

Spinocerebellum: Vermal section
receives input from where?

Answer 4

The spinal cord
Vestibular nuclei
Auditory and vestibular information via the brainstem nuclei

Question 5

Spinocerebellum: vermal section sends output to where?

Answer 5

The vestibular nuclei
Reticular nuclei
Motor cortex via thalamas

Question 6

Spinocerebellum: vermal section sends output to where?

Answer 6

The vestibular nuclei
Reticular nuclei
Motor cortex via thalamus

Question 7

Spinocerebellum: Vermal section output reaches motor neurons via…

Answer 7

The vestibulospinal tracts
Reticulospinal tract
Medial CST

Question 8

Spinocerebellum: paravermal or paramedian section receives input from where?

Answer 8

The spinal cord

Question 9

Spinocerebellum: paravermal or paramedian section sends output to where?

Answer 9

The red nucleus
Motor cortex (via thalamus)

Question 10

Spinocerebellum: paravermal or paramedian section output reaches motor neurons via…

Answer 10

The rubrospinal tract
Lateral CST

Question 11

Cerebrocerebelllum receives input from where?

Answer 11

The cerebral cortex (via the pontine nuclei)

Question 12

Cerebrocerebellum sends output to where?

Answer 12

The motor and premotor cortices:
- dentate nucleus and motor thalamus

Red nucleus

Question 13

Cerebrocerebellum outputs reaches motor neurons via…

Answer 13

Lateral CST and corticobrainstem tracts
Rubrospinal Tract

Question 14

Vestibulocerebellum is in what lobe?

Answer 14

Flocculonodular lobe

Question 15

The Spinocerebellum is located in what region of the cerebellum?

Answer 15

Vermal and paravermal/paramedian section

Question 16

Cerebrocerebellum is located in what regions of the cerebellum?

Answer 16

Lateral cerebellar hemispheres

Question 17

How many lobe does the cerebellum have?

Answer 17

3

Question 18

What are the names of the cerebellar lobes?

Answer 18

Anterior Lobe
Posterior Lobe
Flocculonodular lobe

Question 19

Name the Cerebellar Penduncles?

Answer 19

Superior peduncles
Middle peduncles
Inferior peduncle

Question 20

Describe the Superior Peduncles.

Answer 20

-Primary efferent:
-projects to motor nuclei in thalamus to relay signal to UMN and pre motor cortex (CST/CBT)
-Direct projections to red nucleus (rubrospinal tracts) and superior colliculus

Afferent singles are recieves from spinocerebellar tract

Question 21

Describe the Middle Penducles.

Answer 21

-Afferent input
-input from contralateral pontine nuclei
- Then the pontine nuclei integrates info from cerebral cortex and superior colliculus Afferent singles

Question 22

Describe the middle penduncles.

Answer 22

-Afferent input
-input from contralateral pontine nuclei
- Then the pontine nuclei integrates info from cerebral cortex and superior colliculus

Question 23

Describe the inferior peduncles.

Answer 23

-Contains both Afferent and efferent signals

-Afferent from vestibular nuclei, spinal cord, and brainstem tegmentum (inferior olivary N.)

-Efferent project to vestibular nuclei and reticular formation (vestibulospinal and reticulospinal tracts)

Question 24

Name the Deep cerebellar nuclei.

Answer 24

1. Fastigial nuclei- vermis
2. Globose nuclei and Globose —> form the interposed nuclei- intermediate zone

Don’t Eat Greasy Food

Question 25

Name the functional unit of local neurons within the cerebellum.

Answer 25

-prukinje cell (inhibitory) - Deep nuclear neuron (excitatory)

Question 26

What are the three layers of the cerebellar cortex from outer most to inner most?

Answer 26

- Molecular layer - Purkinje Cell layer - Granular layer

Question 27

The granular layer contains what type of nerve cells?

Answer 27

-Golgi cell - Granule cell

Question 28

Describe the nerve fibers responsible for input.

Answer 28

- mossy fibers -Climbing fibers

Question 29

What are Mossy fibers?

Answer 29

All regions of CNS Axons from pontine nuclei to mossy fibers to granule cell

Question 30

What are climbing fiber cells?

Answer 30

Connects to inferior olivary nucleus and synapses with deep cerebellar nuclear cell and purkinji cell.

Question 31

What nerve cells are responsible for output in the cerebellum?

Answer 31

Purkinje cells and deep nuclei

Question 32

Describe the Purkinje cells function.

Answer 32

Inhibit the cellular and vestibular nuclei

Question 33

Describe the deep nuclei function.

Answer 33

Excitatory output from cerebellum to cortical region