Lec1 Flashcards
(34 cards)
List Infectious agents
Bacteria- fungi- viruses- protozoa- helminths
Some infections are communicable
T/F?
F, Almost all
After the transfer of pathogen to the body apparent symptoms and signs appear after some time.
Incubation period
Infections that don’t result in clear symptoms
Inapparent , latent, subclinical infection
Dangerous sources of infections to other threatening public health
Chronic carriers
Infection occurring at a persistent low level in certain geographic area
Endemic infection
Infection occurring frequently than usual for some time in certain geographical area
Epidemic infection
Infection occurring in worldwide distribution for some time
Pandemic infection
Waxy cell wall of Mycobacterium tuberculosis has high con. of lipids called
Mycolic acids
Resist the diffusion of drugs abd disinfectant inside cell
Mycolic acids
Capsule Limits the ability of phagocytes to engulf bacteria because negative changes on capsule repel positively charged cell membrane.
T /F?
F, negatively
Motile enterobacteria like E.coli causes
Urinary tract infections.
Links the donor and recipient bacteria during conjugation to Facilitate the exchange of virulence gens
Sex pilus
- Resistance to antibiotics
- Resistance to UV
- Resistance to heavy metals
- Production of exotoxins
- Production of becteriocins
Plasmids
Example of bacteriocins useful in treating antibiotics Resistance bacteria
- Colicins made but E.coli
- pyocins made by P.aeruginosa
short DNA sequences of inverted repeats at each end
Domain 1
Transposase gene that mediates the excision and integration processes by expression of transposase enzyme
Domain 2
Repressor gene that regulates the expression of transposase gene and gene 4
Domain 3
Drug resistance gene or toxin production gene
Domain 4
replicate and insert the new copy into another site
Replicative transpsons
excised from their site without replicating and then inserted into new site
Direct transposons
Medical significance of transposons
- Transfer drug resistant enzymes or toxins
- Cause mutation in gene
Medical concerns of spores
- Responsible for resistance of pathogenic bacteria to heat, radiation, chemical.
- Resistance facilitates survival and spread of bacteria between people.
Where dipicolinic acid, a calcium ion chelator found?
In spores