lec1 Flashcards
(18 cards)
behavior
something living organism DOES
- something whole organisms do (not parts or organs)
genes
distinct physical units of inheritance
- sequence of dna (coding regions, etc. functional sequences)
genetics
physical nature of genes
what is a spandrel (both definitions)
sprandel - physical space between arch and another arche (within rectangular space)
bio version → phenotype produced as the bi product of evolution of other characteristics rather than as a direct result of natural selection
behavioral repertoire
set of behaviors characteristic either of an entire species or a single member of a species
- each species has a unique behavioral repertoire
origin of behavior genetics; gregor mendel
discrete units which are passed down
origin of behavior genetics; charles darwin
only successful traits get passed
francis galton
founder of eugenics, fingerprint analysis, twin studies, behavioral genetics, biometry
- physical + behavioral traits → determined by hereditary
- expand darwin to cognitive aspects such as intelligence
- heredity genius → first human behavioral genetic investigation
eugenics movement
promote genetic improvement in population by maintaining to can and cannot reproduce
- ‘highly bred human race’
- strong support from social elites
sexual sterilization of people with undesirable traits (~3000 forced sterilization)
trait improvement (master race) via systemic racial genocide
nature vs nurture (galton and watson)
galton → nature dominates nurture
watson → nurture over nature, take dozen healthy infants and mold them into whatever I want
pavlov and skinner (behaviors are learned)
pavlov → classical conditioning
- quantitative behavior
- condition a response to a stimulus
skinner → operant conditioning
- punishment and reinforced behaviors
but some behaviors are innate (lorenz, frich, tinbergen)
ethology - study of non human behaviors
behavior imprinting - learned behavior independent of consequences (duckies following mommy)
fixed action patterns - instinctive behavior (mating dances)
genetic predisposition
genes or combination of genes that produce specific traits under specific environmental factors / conditions e.g. depression (gene susceptibility)
point mutation (silent, nonsense, missense)
change in one nucleotide
silent = no change in codon, nonsense = stop, missense = change in amino acid
frameshift mutation
changes amino acid sequence by a lot, addition or deletion of 1 or 2 nucleotides in sequence
monoamine oxidase a + antisocial behavior
- Gene on X chromosome controls MAOA (high versus low levels due to variable repeats)
- Those carrying MAOA-L allele and exposed to high maltreatment showed more anti-social behaviour.
- No direct effect of MAOA! This is an example of a Gene x Environment interaction.
psychiatric disorders
definition - clinical significant disturbance in cognition, functionality, behavior
there are no biomarkers for mental illness
psychiatric disorders are based on subjective measures, not objective (etiology)
- most are idiopathic (unknown origin
genetic architecture
refers to the overall composition of the implicated risk variants in the
population—the total number of variants and, for each, the frequencies in those afflicted and in the general population and the degree of risk conferred.