Lec2 Flashcards
(20 cards)
______________is a mixture of two or more components that form a homogenous molecular dispersion. The components are referred to the solute and solvent.
True solution :
__________is the dissolved agent.
Solute
___________is the component in which the solute is dissolved.
Solvent
___________is one in which an equilibrium is established between dissolved and undissolved solute at a defined temperature.
saturated solution:
___________the concentration of solute in a saturated solution at a certain temperature.
Solubility is a quantitative way
________________is a spontaneous interaction of two or more substances to form a homogenous molecular dispersion.
Qualitative definition of solubility
Solubility depends on __________, _________ and ___________ effects that lead to mutual interactions between the solute and the solvent.
chemical, electrical and structural effects
In pre-or early formulation, selection of the most suitable solvent is based on the principle of __________________.
(like dissolved like)
The solubility of a drug can be expressed in terms of ………..
molarity, normality, molality, mole fraction and percentage (w/w%, w/v%, or v/v%).
1g of boric acid dissolves in _____ml of water and _____ml of glycerin.
18ml
4ml
Term :very soluble needs..
Less than 1 part
Freely soluble
1 to 10 parts
Soluble
10 to 30 parts
Sparingly soluble
30 to 100 parts
Slightly soluble
100 to 1000 parts
very slightly soluble
1000 to 10 000 parts
Practically insoluble
more than 10 000 parts
Factors Affecting Solubility:
1-the nature of the solute and solvent
2- temperature
3- pressure
understanding the phenomenon of solubility to__________
to select the best solvent for a drug or a mixture of drugs
Salts and sugar dissolve in water
While naphthalene dissolves in ________
Benzene
