Lecture 1 Flashcards

1
Q

What are the 4 key functions of the GI tract?

A

Motility, secretion, digestion and absorption

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2
Q

What motility occurs in the oral cavity?

A

Chewing and swallowing

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3
Q

What secretion occurs in the oral cavity?

A

Mainly amylase, some lingual lipase and some protease.

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4
Q

What digestion occurs in the oral cavity?

A

Mainly of carbohydrates by salivary amylase. only some digestion of lipids and proteins

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5
Q

Is there any absorption in the oral cavity?

A

No

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6
Q

What is the motility of the oesophagus called?

A

Peristalsis

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7
Q

What are the three types of salivary gland?

A

Parotid, submandibular and sublingual

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8
Q

What type of saliva is secreted by the parotid salivary glands?

A

Watery

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9
Q

What type of saliva is secreted by the sublingual glands?

A

Thick mucus saliva

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10
Q

What type of saliva is secreted by the submandibular glands?

A

Mixture of both watery and mucus

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11
Q

What motility occurs in the stomach?

A

Peristalsis

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12
Q

What do parietal cells secrete?

A

HCl and intrinsic factor

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13
Q

What is the purpose of HCl?

A

Activates pepsin and is antibacterial

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14
Q

What does intrinsic factor do?

A

Complexes with vitamin B12 to aid its absorption

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15
Q

What do chief cells secrete?

A

Pepsinogen and gastric lipase

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16
Q

What does pepsinogen do?

A

Activated by low pH to pepsin for protein digestion

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17
Q

What does gastric lipase do?

A

Digests fat

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18
Q

What do D cells secrete?

A

Somatostatin

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19
Q

What does somatostatin do?

A

Inhibits gastric acid secretion

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20
Q

What do G cells secrete?

A

Gastrin

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21
Q

What does gastrin do?

A

Promotes gastric acid secretion

22
Q

What do mucus neck cells secrete?

A

Mucus and bicarbonate

23
Q

What does mucus do?

A

Physical barrier between epithelium and lumen contents

24
Q

What does bicarbonate do?

A

Buffers gastric acid to protect the epithelium

25
What do ECL cells secrete?
Histamine
26
What is histamine for?
Stimulates gastric acid secretion
27
What 2 main substances are digested in the stomach?
Fats and proteins
28
What can be absorbed in the stomach?
Alcohol and lipid soluble substances/drugs like NSAIDS.
29
What is motility like in the small intestine?
Slow which allows for time for mixing up with enzymes and bicarbonate secretions
30
What organs secrete substances into the small intestine?
The pancreas secretes enzymes and bicarbonate, the gall bladder secretes bile.
31
What secretions occur in small intestines?
Mucus from goblet cells, hormones such as CCK, secretin and GIP
32
What is digested in the small intestines?
Carbohydrates, fats, polypeptides, nucleic acids
33
How are proteins absorbed in the small intestine?
Active transport
34
How is glucose, fructose and amino acids absorbed?
by secondary active transport.
35
How are fats absorbed?
Simple diffusion
36
How are vitamins and minerals absorbed?
Active transport
37
How is water absorbed?
Osmosis
38
What is the main function of the large intestine?
Fluid absorption
39
What is secreted in the large intestine?
Mucus from goblet cells
40
What is the external layer of the GI tract?
Serosa which is connective tissue
41
What are the two layers of muscle?
Longitudinal and circular
42
What nerve plexus sits between the two layers of muscle?
Myenteric plexus
43
What nerve plexus sits below the circular muscle?
Submucosal plexus
44
What layer is below the circular muscle?
Submucosa
45
What is within the submucosa?
Glands
46
What does the myenteric plexus control?
Motility
47
What does the submucosal plexus control?
Secretions from glands
48
What is below the submucosa?
The muscularis mucosa
49
What is under the muscularis mucosa?
Lamina propria
50
What is under the lamina propria?
Epithelium