Lecture 1 Flashcards
What is addiction?
- Loss of control
- Catastrophic consequences
- Decrease in pleasure
Does drug dependence, drug abuse or bad habits equal addiction
NO
What is the definition of addiction?
Addiction is defined as a chronic, relapsing disorder characterized by compulsive drug seeking and use despite adverse consequences. It is considered a brain disorder, because it involves functional changes to brain circuits involved in reward, stress, and self-control, and those changes may last a long time after a person has stopped taking drugs.
This dysfunction is reflected in the addicted individual’s pathological pursuit of the drug, despite serious adverse consequences
What does I-RISA mean?
Impaired Response Inhibition and Salience Attribution
How does the I-RISA model work?
What is the DSM-5 criteria substance use disorder (SUD)?
- Taking the substance in larger amounts or for longer than you’re meant to
- Wanting to cut down or stop using the substance but not managing to
- Spending a lot of time getting, using, or recovering from use of substance
- Cravings and urges to use the substance
- Not managing to do what you should at work, home, or school because of substance
- Continuing to use, even when it causes problems in relationships
- Giving up important social, occupational, or recreational activities because of substance use
- Using substances again and again, even when it puts you in danger
- Continuing to use, even when you know you have a physical or psychological problem that could have been caused or made worse by the substance
- Needing more of the substance to get the effect you want (tolerance)
- Development of withdrawal symptoms, which can be relieved by taking mor of the substance
How many symptoms do you need to have a mild substance use disorder according to the DSM-5?
2-3 symptoms
How many symptoms do you need to have a moderate substance use disorder according to the DSM-5?
4-5 symptoms
How many symptoms do you need to have a severe substance use disorder according to the DSM-5?
6+ symptoms
What similarities does addiction have to what we label a disease?
- It’s treatable
- It’s preventable
- It modifies biology
- Genetics is a major contributor to SUD’s (OUD -60%-80% heritable)
- Using imaging technology, we can see the pathology
Why should you study addiction?
- Understanding addiction can help bridge the gap between science and practice
- Education is key in data driven policy initiatives and stigma reduction
- We need novel treatment and prevention efforts because what we are doing isn’t working
What are the behavioral process of addiction?
- Repetitive, persistent behaviors, where there is an ability to stop despite the negative consequences
- There is a pattern similar to substance use disorders
- Craving, bingeing, tolerance and withdrawal
- There behaviors stimulate endogenous chemicals (neurotransmitters that involve the dopamine pathway for reward learning
