lecture 1 Flashcards
Testing
IRB Animals Cell culture - earliest trial (premolars extraction was planned 1950-1970) (test on duration, stress, and function)
inflammation can be caused by
toxicity
mutagenicity
allergy
allergic reactions and dosage
DOSE INDEPENDENT
inflammation and dosage
DOSE DEPENDENT
edema vs erythema
edema - fluid coming out in cavity
erythema - superficial redness
acute vs chronic
acute - sudden quick
chronic - slow persistent
mutagenic
substance alters DNA bp
irrelvant to mutation
NO dental material is carcinogenic
a
local vs systemic
local - pulp, periodontal, apical, tongue, buccal, labial mucosa
systemic - ingested, inhaled, released at apex, absorption through mucosa, blood/lymph
Enamel is permeable or not?
Permeable tissue
How teeth is bleached - change in color of dentin
(travel thru enamel and reach dentin then oxidize then change color)
precious with nonprecious
precious + nonprecious creates electrick shock -> create galvin reductive reaction -> degrade material
things that can happen to material
corrosion/degradation oxidation (rust) electrochemical mechanical body's response to digestion acidic/alkalic environment
immunotoxicty
lichenoid reaction
plasma cell gingivitis
odonteoblast
start blasting dentin cells -> start from pulp all the way to emanto junction
Periodontal interface
Pocket
JE
PDL - periodontal ligament
cementum
Periapical
apex of tooth root
Dentin-resin interface
chemical and mechnical
leakage
implant-bone interface
osseointegration biointegration (no idea make sure to understand)
MSDS (SDS)
tells you what can happen, potential adverse affect
Berylium
in alloy
Methacrylate
white filling material
esttrogenicity
mutational change in DNA
