Lecture 1 and 2- macromolecules Flashcards
(105 cards)
What are carbohydrates?
Molecules containing carbon atoms flanked by hydrogen atoms and hydroxyl groups (H-C-OH)
What are the two main biochemical roles of carbohydrates?
- Energy source: energy can be released in a usable form
- Carbon skeletons: rearranged to form new molecules for new structures and functions
What are the 4 categories of biochemically important carbohydrates?
- Monosaccharides
- Disaccharides
- Oligosaccharides
- Polysaccharides
What is the general formula of a carbohydrate?
CH2O in the proportion 1:2:1, but this differs in di,oligo and polysaccharides because of the loss of two hydrogens and an oxygen during condensation reactions.
Give an example of some monosaccharides.
Glucose, ribose, fructose (simple sugars)
Give an example of some polysaccharides.
Starch, glycogen, cellulose
What are oligosaccharides?
Carbohydrates made up of several (3-20) monosaccharides.
How are monosaccharides produced?
Green plants produce monosaccharides through photosynthesis
What sugar is in every living cell?
Glucose
What are the two forms of glucose?
Straight chained and ring form
Ring form predominates 99% of the time because it is more stable
What are the two versions of the ring form of glucose?
Alpha and beta- differing by the orientation of the H and OH groups on carbon 1.
These interconvert in equilibrium when dissolved in water
What series of optical isomers do most monosaccharides belong to?
D series (as opposed to the L-series that occur predominantly in amino acids)
Some monosaccharides are structural isomers. What does this mean?
They have the same kinds and numbers of atoms but are in different arrangements.
Give an example of structural isomerism in carbohydrates.
Hexoses- formula C6H12O6
Glucose, fructose, mannose, galactose etc.
Which two pentoses are of particular biological importance?
Ribose, deoxyribose- form part of the backbone of RNA and DNA
What is the difference between ribose and deoxyribose?
NOT isomers
One oxygen atom is missing from the carbon 2 atom of deoxyribose
What is the name of the bonds between monosaccharides?
Glycosidic linkages
What are glycosidic linkages?
Covalent bonds that form between monosaccharides during condensation reactions
Sucrose is a disaccharide formed by the glycosidic linkage of which monosaccharides?
glucose and fructose
Lactose contains which two monomers?
glucose and galactose
What determines the type pf glycosidic linkage between monomers?
alpha linkages form between alpha-D-glucose
beta linkages form between beta-D-glucose
What are the similarities and differences between cellubiose and maltose?
Maltose is produced by alpha linkages between two glucose molecules
Cellubiose is produce by beta linkages
Both are structural isomers
They have different properties
Maltose can be hydrolysed in the human body, cellubiose cannot
Certain microorganisms can break down cellubiose
What are some features of oligosaccharides?
- Some have additional functional groups - special properties
- Often covalently bonded to proteins and lipids on the outer cell surface- recognition signals
Such as human blood types, ABO
What are the functions of polysaccharides?
Energy storage
Structural materials