Lecture 1- Introduction Flashcards

1
Q

3 major components of the MSK

A

bone

muscle

connective tissue

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2
Q

are all skeletal muscles voluntary

A

no- postural

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3
Q

function of bone

A
  • Support
  • Protection

◦Skull

◦Sternum

• Metabolic

◦Calcium and phosphate

• Storage

◦Calcium, phosphate and fat

  • Movement
  • Haematopoiesis

◦In adults
◦In babies liver and spleens

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4
Q

function of skeletal muscle

A
  • Locomotion
  • Posture
  • Metabolic
    • Store glycogen
  • Venous return
    • Deep veins in the legs
    • Pumps blood back up to the heart
  • Heat production
    • E.g. shivering
  • Continence
    • Constant contraction of urethra and anus
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5
Q

function of conenctive tissue

A
  • Tendons
    • Force transmission muscle-bone
      • High amounts of collagen, less elastin
      • Stability of joints
  • Ligaments
    • Support bone-bone
  • Fascia (sheets of connective tissue) ◦Compartmentalisation ◦Protection
    • E.g. deep fasica
    • E.g. think of when we skinned the limbs
  • Cartilage
    • Articular
    • Hyaline
      • Very well hydrated
      • Slippy
      • Blue in colour
      • Decrease friction
  • Fibrocartilage
    • Shock absorption
    • Between the vertebra
    • In the knee
    • Increase bony congruity
  • Synovial membrane
    • Secretes synovial
  • Bursa
    • Synovial fluid-filled sacs to protect tendons, ligaments etc from friction
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6
Q

tendon

A

Force transmission muscle-bone

‣ High amounts of collagen, less elastin

‣ Stability of joints

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7
Q

ligaments

A

supports bone to bone

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8
Q

fascia

A

◦Compartmentalisation ◦Protection

‣ E.g. deep fasica
◦E.g. think of when we skinned the limbs

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9
Q

cartilage: articular

A

Hyaline
• Very well hydrated

  • Slippy
  • Blue in colour

‣ Decrease friction

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10
Q

cartilage: fibrocartilage

A

Shock absorption

Between the vertebra

In the knee

‣ Increase bony congruity

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11
Q

synovial membrane

A

secrete synovial fluid

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12
Q
A
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13
Q

bursa

A

synovial fluid- filled sacs to protect tendons, ligaments etc friction

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14
Q

bone connective tissue

A

ECM- fibres and ground substance

  • In bone calcified - CaPO4(gives bone strength)

Bone is dense connective tissue

  • Osteocytes
  • Osteoblasts
  • Osteoclasts
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15
Q
A
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16
Q

osteoblasts

A

lay down osteoid and build bone

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17
Q

how do osteoblasts build bone

A

Lay down bone and step back, lay down bone and step back

Traps osteoblasts in osteoid that is calcified—> osteocytes (trapped osteoblast in lacunae

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18
Q

osteocytes communicate via

A

via cytoplasmic processes (think cannuculi )

◦Transmit signals

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19
Q

osteocytes are important for

A

sensing stresses and strains in the bone

◦Will cause growth

◦Why exercise helps build bone

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20
Q

osteoblasts

A

◦Multinucleated
◦Related to macrophages
◦Release acidic substances and dissolve the bone —> releasing calcium

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21
Q

cortical bone strucutre (compact bone)

A

◦A bunch of pencils being held together ◦Haversion and volkmanns canals

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22
Q
A
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23
Q

classification of bone

A

long

short

flat

sesamoid

irregular

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24
Q

long bone

A

◦Bone longer than wide

◦Very good lever

◦Humerus

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25
short
◦Bone as long as wide ◦Tarsals ◦Work together to give a range of movement ◦Gives points of attachment to for ligaments and tendons
26
flat
intramembranous ossification ◦For protection ◦Skull ◦Sternum
27
sesmoid
◦Protects tendons ◦E.g. patella ◦Shaped like a sesame seed
28
irregular
vetebra
29
bony prominences- muscle attachments
Areas where bones are close to the surface (called "bony prominences") and areas that are under the most pressure are at greatest risk for developing pressure sores.
30
body prominences size
* Their size tells us about the muscle that attaches to it * Small- not a powerful muscle that attaches * If big site- must be a powerful muscle that attaches
31
32
grooves
related to nerves - impression on bones- no free space in body
33
bone blood supply
each bone has multiple blood supply
34
Depending of let right dominance, bone will be
thicker in dominant arm/ leg • very dynamic ◦Due to osteoclasts and blasts
35
joints
Connects one bone to another * Great variation in range of movement * Highest risk of dislocation * Range of movement versus stability
36
classification of joint
- fibrous - cartilaginous - synovial joints
37
fibrous joints
◦Two bones glued to eachother using collagen ◦Won’t move very much ◦For areas that need great stability and strands e.g. teeth and skull
38
cartilaginous joint
◦Glue is cartilage (more flexib;e than pure collagen fibres) ‣ Limited mobility (more than fibrous) ‣ Found at end of growing bones or along the midline of the body ◦Sites of growth e.g. epiphyseal plate
39
synovial joint
◦Separates bones are capped by smooth articulate cartilage with a thin film of synovial fluid separating them ‣ Secreted by synovial membrane ◦Like egg white ◦Frequently highly mobile ◦Found all over the skeleton
40
41
classification of synovial joints
plane joint hinge joint pivot saddle condyloid ball and socket
42
plane joint
Two flat surfaces sliding over eachother ‣ E.g. in the foot (tarsals)
43
hinge
◦Moving in a single plane ◦E.g. elbow
44
pivot
rotational
45
saddle
◦Between thumb and carpal ◦Constrained motion ◦Two different planes of movement
46
condyloid
◦In the wrist ◦Eclipse shaped joint ◦Alllows flexion and extension ◦No rotation of the the wrist
47
ball and socket
◦Hip and shoulder ◦Round head of femur moving into another joint ◦Allows movement in many planes
48
development of synovial joints using knee as an example
Arise form cartilage models of bone (hyaline) 1) Where joints form a load of chondrocytes die and leave a gap 2) Perichodnrium remains and forms the capsule of the joint and contributes to
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50
joints as levers
- first-class lever - second-class lever - third-class lever
51
Mechanical advantage Ardvark long olecranon * On the right * For strength for digging Sloth- short olecranon * Don’t need as much strength
52
The origin is usually the
stationary proximal anchord pointt
53
The insertion is usually the
mobile distal attachment point
54
characteristic of muscle contractin
Muscle contraction is symmetrical exerting equal force on origin and insertion
55
muscles can only
PULL THEY CANNOT PUSH
56
Muscles can onyl act on the
joints they cross
57
the action of a muscle on a joint is a function of the
orientation of its fibres of those fibres to the joints
58
muscles work ...... and almost never in...
◦Muscle work together and almost NEVER in isolation ‣ CNS coordinates
59
types of contraction
Concentric concraction Eccentric contraction Isometric contraction
60
Concentric contraction
muscle pull while shortening (e..g bicep curls)
61
Eccentric contraction
Muncle puls while lengthening (knee extensors walking downhill)
62
Isometric contraction
muscle pulls while staying same length (carrying a load)
63
muscles can
1) shortens 2) lengthens 3) stays the same always pullling
64
muscles are found within
``` within fascia (deep) compartments ◦The muscles within a compartment share a common innervation and action (generally) ``` ◦Same nerve supply and blood supply ◦Just need to learn one nerve
65
types of muscles
parallel fusiform sphincter triangular pennate
66
parallel muscle
lengthen and not always that powerful
67
fusiform
◦Can fit in more muscle fibres ◦More powerful
68
sphincter
◦Parallel muscle bent into a circle ◦To close things ‣ Eye ‣ Anus
69
triangular muscle
◦Deltoid ◦Gives more diversity in action
70
pennate (feather)
Can’t shorten (as much as parallel) much but have loads fo muscle fibres meaning they are very powerful
71
predicting muscle action
where does it attach? how many joints does it cross? how is it related to the joints? what direction do the fibres run in?
72
connective tissue are
All physically connected to eachother Continuity between periosteum, joint capsule, tendon, epimysium and bone collagen matrix
73
Anatomists and histologists have different names for different things...Superficial fascia=
subcutaneous fat
74
deep fascia=
epimysium of muscle
75
name the fascia of the thigh
fascia lataa - deep dascia
76
tendons
• parallel collagen fibres connecting muscles to bones
77
ligaments
* Connects bone to bone * Develops from perichondrium * Usually thickening of the connective tissue * Limit movement
78
aponeurosis
Flattened tendon (sheet like) in the head Abdominal wall (no muscle- richi collagen) Plantar fascia (plantar aponeurosis)
79
innervation of joints- Hiltons law
the innervation of joints is the same as the muscle and skin over the sites of insertion
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81
Basic principles of musculoskeletal development- Body segmentation due to which gene
HOX gene
82
homeostatic mustants 1
• some people have 6 lumbar instead of 5
83
homeostatic mutant 2
extra-fingers- polydactyl
84
homeostatic mutant 3
extra cervical rib --\>man compress vessels/ nerves
85
the power of serial homologus
86
upper limbs rotate..
out 90 decreases
87
lower limbs rotates
in 90 degrees