Lecture 1: Pathological Basis Flashcards
(23 cards)
What are the five layers of the epidermis?
Stratum corneum, granulosum, spinosum, basale, basement membrane
Approx how long does it take to heal the epidermis?
1 month
Why does epidermis take a long time to heal?
No blood vessels - relies on dermis
Which layers of the skin have nerves?
Dermis
What are the three plexi of blood vessels in the skin?
Superficial, middle and deep dermis
What are the two main glands in the skin?
Sebaceous and apocrine (sweat)
What is the most common hair follicle phase?
Telogen (resting)
WHich layer is thickened in hyperkeratosis?
Stratum corneum
What is the difference between orthokeratotic and parakeratotic hyperkeratosis?
Orthokeratotic has no nuclei in stratum corneum, parakeratotic does have nuclei
Which layer is thickened in acanthosis?
Spinosum
What are the projections called in acanthosis?
Rete pegs
What is exocytosis?
Leucocytes in the epidermis
What is seborrhea sicca?
Scaly, hyperkeratosis
What is seborrhea oligosa?
Lots of glandular production
What is seborrhea?
Increased epidermal cell turnover, keratin scales, acanthosis
What is acantholysis?
Separation of cells of prickle cell layer
What is pigmentary incontinence?
Melanin phagocytosed by macrophages in upper dermis
What is panniculitis?
Inflammation in subcutaneous fat
What is adenitis?
Inflammation of skin glands
Which deficiency can cause depigmentation?
Cu
What is the usual cause of follicular casts in an older animal?
2ry to something else
What causes an epidermal collarette?
2ry lesion after pustule bursts
What kind of virus causes hydropic degeneration?
Poxvirus
