Lecture 12 Flashcards Preview

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Flashcards in Lecture 12 Deck (6)
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0
Q

Metastasis kills patients __% of the time?

A

90%

1
Q

Micrometasteses are smaller than __

A

2mm

2
Q

What % of circulating tumor cells successfully initiate a metastatic focus?

A

Less than 0.01%

3
Q

What helps cancer cells invade tissues by cutting BM and ECM?

A

Matrix metalloproteinases (MMPs)

4
Q

What metal ion is required for MMPs’ catalytic activities?

A

Zinc

5
Q

What is the rate limiting step of metastasis?

A

Colonization