Lecture 13 Flashcards

(43 cards)

1
Q

proceptivity and the menstrual cycle in humans

A

female more likely to show initiation during ovulatory period and follicular period

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2
Q

in postmenopausal women estrogen replacement ___

A

increases libido

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3
Q

in naturally cycling women estrogen is positively associated with

A
  • sexual desire
  • sexual attraction to men other than one’s primary partner
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4
Q

female pacing of copulation

A

when female has control over when the intermissions occur during a mating test

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5
Q

in paced paired mating tests females return to the male…

A

more slowly following ejaculation compared with mounts or intromissions

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6
Q

what follows intromissions

A

prolactin release –> corpora lutea support –> enables implantation of the blastocyst

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6
Q

pacing and multiple intromissions

A

slower pacing of intromission in the paced test optimizes reproduction

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7
Q

what happens if the female doesn’t have significant number of intromissions?

A

the wall cannot build up and eggs cannot implant successfully

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8
Q

menstruation bleeding

A
  • due to steroid deprivation
  • occurs when E and P are at baseline
  • without steroid support the endometrial layer sloughs off and blood vessels leak blood
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9
Q

what strengthens the uterine walls?

A

intromission stimulation of prolactin release

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10
Q

when do estrogen levels peak

A

at time of ovulation

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10
Q

why does progesterone peak later

A

due to formation of corpora lutea, continues to remain high during luteal phase, if pregnancy not achieved the progesterone levels drop off

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11
Q

proestrus bleeding

A
  • due to steroid stimulation
  • dogs/some other mammals discharge blood during proestrus
  • due to estrogen-induced stimulation of the uterine wall causing rapid growth which tears blood vessels
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12
Q

induced ovulation in prairie voles

A

if a male is present
- anogenital investigation
- exposure to male urine
- VNO –> main olfactory bulb –> release of GnRH
- stimulates release of LH (possibly FSH) 1 hour post-exposure
- within 24 hours gonadotropin release has stimulated estrogen release and the onset of estrous behavior
- approx 12 hours following copulation, ovulation occurs

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13
Q

Lee-Boot effect

A

estrous cycle lengthens in all female mice when they all live together, female-released chemosensory cue that is released and detected by females leading to a longer estrous cycle

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13
Q

Bruce effect

A

pregnant females exposed to not-sire male for at least 2 days, presence of chemosensory cues from males cause GnRH release and behavioral estrus onset, females abort or resorb their fetuses

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14
Q

Whitten effect

A

chemosensory cues from male that impact female hormonal status, induces estrous behavior within 48 hours of introducing male into all female living environment, male urine causes GnRH release

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15
Q

Vandenbergh effect

A

juvenile female around grown male, earlier onset of puberty in females, females exposed to lots of adult females delays onset of cylce

16
Q

pheromones and the human menstrual cycle

A

evidence for human pheromone release and detection among women, can impact the menstrual cycle of other women

17
Q

results of female pheromone experiment

A
  • women exposed to odors of women in follicular phase had a reduced length of cycle shortened by about 2 days
  • women exposed to odors of women in ovulatory phase had an increased length of cycle by about 1.5 days
18
Q

female pheromone experiment

A
  • absorbent pads under arms for Dif stages of menstrual cycle
  • experimenters took pads and froze them
  • new cohort of women would rub frozen pads under noses
  • new women exposed to pheromones released onto pads from first group of women
  • looked at menstrual cycles of second group of women
19
Q

stress and the menstrual cycle

A

high stress levels = irregular menstrual cycles, strong association between stress and dysmenorrhea

20
Q

McClintock effect

A

study of undergraduate women living in dorms, menstrual synchronization more likely in roommates, took about 7-8 months of cohabitation before synchronicity occurred

21
Q

nutrition and the menstrual cycle

A

both inadequate diet, or habitual hyper caloric food consumption affect ovarian function and decrease fertility

22
illness and the menstrual cycle
systemic disease or localized infection: lethargy, hyperosmnia, malaise, anorexia, loss of interest, lack of goal-directed behavior
23
IL-1B treatment
reduced attractivity of females, but not males - males spend less time with females when females looked sick (reduced attractivity of females) - females spent same a mount of time with males no matter how sick they looked (no loss of attractivity)
24
kisspeptin cells in rats
- express estrogen receptors - receive SCN input - activated during GnRH/LH surge
25
SCN input in rats
important for circadian rhythm distinction leading to ovulation
26
HPG axis
hypothalamic pituitary gonadal axis
27
activation of kisspeptin cells in primates
neuroestradiol contributes to activation of kisspeptin cells which drive the LH surge and ovulation
28
neuroestradiol
- also acts in concert with kisspeptin neurons - estradiol from body + locally produced estradiol works to turn on kisspeptin neurons, leads to LH surge
29
anterior hypothalamus
lesions in marmosets abolished preceptive behaviors (tongue-flicking and staring) without affecting receptive behavior (no difference in mounts they refused or terminated)
30
ventromedial hypothalamus (VMH)
40-50% of VMH cells showed activation during presentation behaviors and throughout copulation
31
MPOA
- during presentation behavior without copulation 40% of cells showed inhibition - during presentation behavior with mating and during copulation up to 90% of cells showed excitation
32
self-stimulation of the clitoris, vagina, and nipples resulted in activation of
paracentral lobule, genital region of the primary sensory cortex
33
orgasm (self-stimulated or partner-stimulated) resulted in activation of
- paraventricular nucleus of the hypothalamus - periaqueductal grey - hippocampus - cerebellum - nucleus accumbens - insula and cingulate cortices - amygdala
34
imagined genital or nipple stimulation activated the
paracentral lobule
35
imagined penetrative dildo stimulation activated the
paracentral lobule, SSC, hippocampus, amygdala, insula, nucleus accumbens, mPFC
36
imagined speculum stimulation activated the
control for nonerotic vaginal stimulation showed minimal brain activation
37
which adrenal hormones increased as a result of arousal
adrenaline and noradrenaline increased, no change in cortisol levels
38
which pituitary hormones increased as a result of arousal
prolactin and LH
39
which gonadal hormones increased as a result of arousal
none: estrogen, testosterone, progesterone unchanged following arousal
40