Lecture 14: Fibrous Connective Tissue Flashcards
(14 cards)
1
Q
Functions of Connective Tissues
A
- structural framework of the body
- supports and interconnects other tissues
- also: protection, NRG storage, transport, defense
2
Q
Fibrous components of the Extracellular Matrix of CT (2)
A
- elastin –> stretchable fiber
2. reticular fibers –> forms supportive meshwork
3
Q
Type-1 Collagen Fibers
A
- aligned and crosslinked to inc. tensile strength
diseases: Scurvy and Ehlers-Danlos Syndrome
4
Q
Amorphous Ground Substance components of Extracellular Matrix of CT (4)
A
- proteogylcans –> sulfates
- hyaluronan
- glycoproteins –> cytokines, growth factors
- extracellular proenzymes
5
Q
Embryonic Connective Tissue
A
- rich in extracellular matrix and mesenchymal stem cells
- in umbilical cord (Wharton’s Jelly)
6
Q
Loose Connective Tissue
A
- areolar
- support and bind other tissues, defend from infection
- found immediately beneath membranous epithelia (lamina propria)
7
Q
Adipose Connective Tissue
A
- loose CT
- abundant adipocytes and sparse ECM
- reserve energy source and insulates against heat loss
- padding/cushioning organs
8
Q
Brown vs White Fat
A
White - energy storage, insulation, cushioning
Brown - key thermogenic tissue, abundant in newborns
9
Q
Reticular Connective Tissue
A
- loose CT
- rich in RETICULAR FIBERS
- open framework = labyrinth for holding free cells
- houses blood cells and immune cells outside of blood/lymphatic vessels
10
Q
Dense Irregular Connective Tissue
A
- extracellular membrane tightly packed
- FIBROBLASTS are principle cell type
11
Q
Dense Regular Connective Tissue
A
- ECM tightly packed
- FIBROBLASTS are principle cell type
- resists pulling forces, poorly vascularized
- in tendons, ligaments, aponeuroses, dense fascia
12
Q
Elastic Connective Tissue
A
- Dense connective tissue
- ELASTIC FIBERS are principle cell type
- allows recoil of tissue following stretching
- in blood vessel walls, bronchiole tubes, special ligaments
13
Q
What is Marfan’s Syndrome?
A
- autosomal dominant (weak elastin –> mutation in fibrillin-1 gene)
- targets: ocular, skeletal, cardiovascular systems
- tall with long arms and legs
14
Q
What is the purpose of fibroblast cells?
A
- produce collagen, elastin, reticular fibers, proteoglycans, and glycoproteins in ECM
