lecture Flashcards

1
Q

Functions of the Skeletal System:

A
  1. Support
    The bones form the body’s supporting framework.
  2. Protects vital organs such as the brain, the heart and lungs.
  3. Movement
    As muscles contract, they pull on bones and therefore,
    move them.
    4.Hemopoiesis/Hematopoiesis – blood cell formation in the red bone marrow
  4. Storage of calcium and phosphorus
    Calcitonin, secreted by the thyroid gland, enhances incorporation of calcium into bone.
    Parathyroid hormone, secreted by the parathyroid gland, regulates the release of calcium from bone.
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2
Q

Types Of Bones - According To Shape

A
  1. Long Bones - longer than wide
    Examples: femur, humerus
  2. Short Bones – roughly with equal dimensions of length and width
    Example: carpal bones
  3. Flat Bones - thin and broad
    Example: skull bones
  4. Irregular Bones - with complex shape
    Example: vertebral bones
  5. Sesamoid Bone – small, round bone embedded within a tendon
    Example: patella
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3
Q

Structure Of A Long Bone

A
  1. Diaphysis
    shaft of long bone hollow tube made of hard, compact bone but light in weight to permit easy movement
  2. Medullary Cavity
    hollow area inside the diaphysis containing yellow fat bone marrow

3.Epiphysis – expanded ends of long bones composed of spongy bone with red bone marrow
4. Articular Cartilage – thin layer of cartilage covering the epiphyses
acts as a cushion between bones in a joint
5. Periosteum- strong fibrous membrane covering the shaft of long bones
6. Endosteum –membrane that lines the medullary cavity

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4
Q

What are the 2 major types of connective tissues in the bone:

A
  1. Compact Bone - the hard and dense outer layer of bone
  2. Spongy Bone – the porous or cancellous bone at the ends of long bones
    . Trabeculae (Latin “trabeculae” – small beam) – needle-like threads of spongy bone
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5
Q

What is an Osteon also called Haversian

A

Osteon or Haversian system– the smallest functional and structural unit of compact bone

. Each circular, tube-like osteon has a central canal that contains a blood vessel. Layers of calcified circular matrix around the central canal are called concentric lamellae (Latin “lamella”- layer)

. Osteocytes or bone cells lie in between lamellae inside little spaces called lacunae (Latin “lacuna” – hole, pit)

.Canaliculi or tiny passageways from the central canal - supply food and oxygen to the osteocytes; connect the osteocytes

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6
Q

What is concentric lamellae?

A

Layers of calcified
circular matrix around the central canal are called
concentric lamellae

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7
Q

What is an Osteocytes also called bone cells

A

Osteocytes or bone cells lie in between lamellae inside little spaces called lacunae (Latin “lacuna” – hole, pit)

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8
Q

Canaliculi or tiny passageways from the central canal

A
  • supply food and oxygen to the osteocytes; connect the osteocytes
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9
Q

What is CARTILAGE & where are chondrocytes located?

A

– connective tissue with collagenous fibers imbedded in firm gel matrix

.Chondrocytes – cartilage cells that are located in lacunae
.Lack of blood vessels in cartilage makes post injury healing rather slow

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10
Q

Endochondral Ossification

A

– formation of bone
from cartilage

. Begins before birth of an infant wherein calcium is laid on cartilage by bone-forming cells called osteoblasts
. Blood vessels invade the diaphysis and ossification centers appear in epiphyses
. Simultaneous action of the osteoclasts, bone-reabsorbing cells, helps sculpture bone into its adult size and shape

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11
Q

Epiphyseal Plate (growth plate) & Epiphyseal line

A

– contains cartilage
from where bone continues to develop and grow

Epiphyseal Line - results when the epiphyseal
plate has ossified with the
resultant cessation of bone
growth

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12
Q

Bone Repair

A

After a fracture, bones heal as long as the circulatory
supply and cellular components of the periosteum and
endosteum survive.

Stages of Healing of a Simple Bone Fracture:
1. Hematoma Formation
2. Fibrocartilagenous callus
3. Bony callus-formation
4. Remodeling

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13
Q

Hematoma Formation (Bone Repair)

A

Blood vessels are broken causing bleeding, pooling and clotting of blood into the fractured bone – a fracture hematoma is formed.

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14
Q

Fibrocartilagenous callus formation (Bone Repair)

A

formation. Cells from the
periosteum and endosteum migrate into the fracture zone. These cells (fibroblasts) convert into osteoblasts which,
together with the osteoclasts,begin reconstruction of
bone.The cells form a thickening (callus) around the fractureand some transform into cartilage-producing cells.
Capillaries grow in the fracture site.

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15
Q

Bony callus-formation (Bone Repair)

A

Continued migration and proliferation of osteoblasts and osteocytes result in turning the fibrocartilagenous callus into bony callus.

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16
Q

Remodeling (Bone Repair)

A

The bony callus will smoothen and be
remodeled through the action of the osteoclasts.

After repair, the fractured bone will be “good as
new” although slightly thicker than normal.

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17
Q

Axial Skeleton

A

-bones at the center or the axis of the body; includes the skull, spine, chest and hyoid bone

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18
Q

Appendicular Skeleton

A
  • bones of the upper and lower extremities (appendages) including the pectoral and pelvic girdles
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19
Q

Bones of the Axial Skeleton

A
  1. Frontal Bone – forehead bone
  2. Parietal Bones (Latin “parietalis” –wall of a cavity) form the topsides or roof of the cranium
  3. Temporal Bones – form the lower sides of the cranium; contain the middle and inner ears
  4. Occipital Bone (Latin “occiput” – posterior and inferior) – bone forming the back of the skull
  5. Sphenoid Bone –forms central part of floor of cranium; forms the sella turcica which holds the pituitary gland
  6. Ethmoid Bone - uniquely-shaped bone that forms floor of cranium, part of the orbit, sidewalls and roof of the nose and part of its middle partition
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20
Q

Bones of the Face

A
  1. Zygomatic bone(Greek “zygoma” - yoke) - cheek bone
  2. Maxilla – upper jaw
  3. Mandible – lower jaw
  4. Nasal – bones that form the upper part of bridge of nose
  5. Lacrimal – medial wall of eye socket and side wall of nasal cavity
  6. Vomer – forms lower, back part of nasal septum
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21
Q

The Vertebral (Spinal)Column:
Total bones of spinal column = 26

A

7 Cervical Bones – Atlas (1st cervical), Axis (2nd cervical)
12 Thoracic - upper back
5 Lumbar - lower back
5 Sacral bones fused into one among adults to form the sacrum
3-5 Coccygeal bones fused into one among adults to form the tailbone

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22
Q

thoracic cage or
chest cage

A

is made up of the 12 pairs of
ribs, the sternum and the thoracic vertebrae.

.The first 7 pairs of ribs are true ribs. They are attached
to the sternum by costal cartilages.
.The lower 5 pairs are false ribs. The 8th, 9th and 10th
ribs are attached to the sternum through the costal
cartilage of the 7th rib.
.The 2 last pairs that are not attached to the sternum (11th and 12th) are floating ribs.

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23
Q

Sternum

A
  1. manubrium -
    uppermost part
    attached to the
    clavicle
  2. body - of the
    sternum
  3. xiphoid -
    process
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24
Q

Appendicular Skeleton

A

The bones of upper and lower extremities together
with the pectoral and pelvic girdles comprise
the appendicular skeleton.

The pectoral girdle - attaches the bones of the upper extremities to the axial skeleton. The scapula (shoulder blade) and the clavicle (collar bone) comprise the
pectoral girdle.

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25
sternoclavicular joint
is the point of attachment between the bones of the pectoral girdle and the axial skeleton
26
Bones of the Upper Extremities
Humerus – arm bone Radius – forearm bone on the side of the thumb Ulna – forearm bone on the side of the little finger Carpal Bones –wrist bones, 8 on each wrist Metacarpals – bones of the palm, 5 on each hand Phalanges – finger bones, 14 on each hand
27
The Pelvic Girdle
The pelvic girdle attaches the bones of the lower extremity to the axial skeleton. The ilium, ischium and pubis comprise the pelvic girdle (hip). The pelvic girdle is attached to the axial skeleton through the sacrum. The femur (thigh bone) is attached to the pelvic girdle through the acetabulum, a socket at the hip joint formed by the three hip bones.
28
iliosacral joint
iliosacral joint attaches bones of the lower extremities to the axial skeleton.
29
Bones of the Lower Extremity
Femur – thigh bone; longest, strongest bone of the body Tibia – shinbone Fibula – calf bone Patella – knee cap Tarsal bones – bones of the ankle joint, 7 on each ankle Metatarsal bones – foot bones, 5 on each foot Phalanges – toe bones, 14 on each foot
30
JOINTS (ARTICULATIONS)
.Connection of a bone to another bone .Hold bones together securely while making movements possible
31
Three types of joints according to the degree of movement they allow:
1. Synarthroses – no movement 2. Amphiarthroses – slight movement 3. Diarthroses – free movement
32
Synarthrosis
fibrous connective tissue grows in between the articulating bones; no movement is allowed Example: skull joints (sutures) coronal suture sagittal suture lambdoidal suture squamous suture
33
Amphiarthrosis
.cartilage connects the articulating bones .some movement is allowed Examples: symphysis pubis, joint between vertebral bones
34
Diarthrosis
–freely movable joints with the following structural features: . Joint capsule . Joint cavity . Articular cartilage . Ligaments . Synovial Membrane . Bursa . meniscus (meniscus - crescent)
35
Joint capsule
– toughest fibrous connective tissue that securely joins the bones in a joint
36
Joint cavity
– space inside the capsule lined with synovial membrane that secretes synovial fluid
37
Articular cartilage
– covers the ends of the bones acting as rubber cushion to absorb shock and help reduce friction during movement Examples: knee joint, elbow joint
38
Ligaments
– cords similarly made of strongest fibrous connective tissue growing out of the periosteum, securing the bones together more firmly
39
Synovial Membrane
– lines the joint space and secretes synovial fluid that acts like a lubricant allowing easier joint movement with less friction
40
Bursa
– a fluid-filled pouch-like extension of the synovial membrane that acts like a shock-absorbing cushion in the joint
41
meniscus (meniscus – crescent)
is a shock-absorbing fibrocartilage pad lying between 2 opposing articular surfaces. . Increases the area of contact between bones . Distributes pressure better . Limits extreme movements
42
Types of Diarthrotic Joints
. Gliding joint . Hinge Joint . Saddle joint . Pivot joint . Condyloid joint . Ball-and-Socket Joint
43
Gliding joint
– least movable, allows limited gliding movements Example: joint between the clavicle and the manubrium
44
Hinge Joint
– allows movement on only 2 directions – flexion and extension -- like opening and closing of a door Example: knee joint, elbow joint, finger joints
45
Saddle joint
The only saddle joint in the body is between the first metacarpal bone and the trapezium of the carpal joint. - Allows flexion, extension, abduction, adduction and circumduction so that the thumb may be opposed to the fingers
46
Pivot joint
Where a small projection of one bone pivots in an arch of another bone allowing pivotal (rotational) movement of the joint Example: joint between the atlas (first cervical vertebra) and the axis (second cervical vertebra)
47
Atlas (C1) and Axis (C2)
The configuration and relationship between the atlas and axis allow the head to attain rotational movement.
48
Condyloid joint
Where the condyloid (oval projection) of a bone fits into an elliptical socket. Example: joint between radius and carpal bones
49
Ball-and-Socket Joint
– the ball-shaped head of one bone fits into a concave socket of another bone - allows the widest range of movement Example: hip joint, shoulder joint
50
Disorders of Bones
1. Fracture 2. Osteoporosis 3. Osteomyelitis 4. Bone Tumors
51
Fracture
– a break in bone often caused by high impact or stress on bone - may likewise be caused by medical conditions like osteoporosis, cancer or osteogenesis imperfecta
52
Osteoporosis
– a bone disease of advancing age characterized by loss of calcified matrix and collagenous fibers from bone - reduction in new bone growth results in bone degeneration and “spontaneous fractures”
53
Osteomyelitis
– inflammation of the bone and bone marrow usually due to a bacterial infection - may occur as a complication of trauma or surgery, or may be blood-borne from another body site
54
Bone Tumors
– mass of tissue that is formed when bone cells proliferate uncontrollably Most bone tumors are benign. 1. Osteochondroma 2. Osteoid Osteoma 3. Osteosarcoma ( Osteogenic Sarcoma) 4. Chondrosarcoma 5. Abnormalities in Spinal Curvatures Scoliosis 6. Skeletal Changes in Aging aside from Osteoporosis 6.1 Lipping 6.2 Osteoarthritis
55
Osteochondroma
– most common benign bone tumor that usually develops during childhood and adolescence - caused by overgrowth of bone and cartilage cells near the growth plat
56
Osteoid Osteoma
– benign tumor that arises from the osteoblasts, occurring mostly in long bones - peak age incidence is during the early twenties
57
Osteosarcoma ( Osteogenic Sarcoma)
– most common malignant tumor of bone caused by proliferation of osteoblasts - teenagers are the most commonly affected age group
58
Chondrosarcoma
– bone cancer that begins from cartilage cells - often affecting people between 40 and 70 years
59
Abnormalities in Spinal Curvatures Scoliosis
- sideways curve of the spine that usually assumes an ‘S’ or a ‘C’ shape Kyphosis –abnormally rounded upper curvature of the spine Lordosis (Swayback)– spine curves inward at the lower back
60
Lipping
– a process wherein aging bones develop indistinct, shaggy-appearing margins with spurs - restricts movement because of piling up of bone tissue around the joints
61
Osteoarthritis
– degenerative joint disease caused by inflammation, breakdown and eventual loss of cartilage in joints
62
Disorders of Joints
1. Dislocation (Luxation) 2. Sprain 3. Arthritis -Osteoarthritis -Rheumatoid Arthritis -Gouty Arthritis or Gout 4. Disorders of the Intervertebral Discs - Degenerative Disc Disease - Disc Herniation 5. Bursitis
63
Dislocation (Luxation)
- when bones in a joint become displaced or misaligned usually caused by sudden impact to the joint
64
Sprain
– joint injury caused by violent twisting of a ligament
65
Arthritis – joint inflammation
Osteoarthritis – degenerative joint disease caused by inflammation, breakdown and eventual loss of cartilage in joints Rheumatoid Arthritis – a chronic autoimmune disease with an unknown cause Gouty Arthritis or Gout – joint inflammation due to excessive amounts of uric acid that form crystals in joints
66
Disorders of the Intervertebral Discs
. Degenerative Disc Disease – a natural part of aging when the disc undergoes structural deterioration, loses ability to cushion the vertebrae - may not cause pain or may cause intractable back pain . Disc Herniation – occurs when the disc prolapses out of its anatomical position due to injury or aging - can cause back or neck pain, numbness or tingling in the arms, or searing pain down one or both legs
67
Bursitis
– inflammation of a bursa caused by irritation, injury or infection